论著-头颈部
胃腺癌临床分期盆腔CT扫描价值及必要性探讨
作者:李 靖1,2 沈 晶1 伍建林1
所属单位:1.大连大学附属中山医院放射科 (辽宁 大连 116001) 2.大连大学临床医学院 (辽宁 大连 116001)
PDF摘要
目的评估盆腔CT扫描在胃腺癌 临床分期中的价值与必要性及胃腺癌盆腔 CT出现转移性病灶的相关因素。方法 收 集2013年1月至2017年7月我院经病理证实 且于治疗前行全腹CT检查(包含盆腔CT)的 胃腺癌202例。查阅报告和CT图像记录盆 腔CT检出的异常改变,将其分为转移相关 与非转移相关两大类,前者再分类为孤立 性或非孤立性转移灶,孤立性者定义为在 盆腔外其他部位未发现转移灶。同时,比 较不同部位胃腺癌患者以及平扫与增强 CT检查对盆腔CT转移性病灶检出率的影 响,并经统计学分析,以P?0.05为差异有 统计学意义。结果 本组202例中有45例 (22.3%)盆腔CT发现异常征象,最常见盆 腔积液(17例,占8.4%)。检出盆腔转移性 病灶7例(3.5%, 95% CI 0.9%-6%),包括 骨转移2例、腹膜结节状增厚1例、淋巴结 增大1例、直肠-乙状结肠肠壁增厚1例、 皮下软组织结节2例,其中孤立性盆腔转 移灶4例(2.0%, 95%CI 0.1%-3.9%)。发生 于不同部位的胃腺癌以及平扫与增强CT对 盆腔转移灶的检出率差异无统计学意义 (P=0.816, P=0.650, P=0.851)。结论 综 合考虑医疗成本、辐射剂量及实际的应用 效果,在胃腺癌治疗前影像学检查中不建 议常规应用盆腔CT检查,可在临床怀疑有 盆腔异常时加以选择。
Objective The objective of this study was to evaluate the value and necessity of pelvic CT examination in gastric cancer (GC) staging. Methods We reviewed the medical records of pathologically proved GC patients who had abdominopelvic CT examination for staging at our institution from January 2013 through July 2017. These pathology findings seen in the pelvis were classified into 2 categories as metastatic disease or not. Metastatic diseases were further categorized as isolated pelvis metastasis or not, and isolated pelvis metastasis was defined as the presence of pelvis metastasis without any other sites of metastasis on CT scan. Comparisons of incidence of pelvis metastases between patients with GC located in different stomach sites and between patients with enhanced CT and with non-enhanced CT were performed. Results A total of 202 patients with GC received abdominopelvic CT examinations at our institution during study period. 22.3% (n=45) of patients had findings in the pelvis, and the most common was ascites (8.4%, n=17). The metastatic diseases in pelvis were found in 3.5% (95%CI 0.9%-6%, n=7) of patients, including bone lesions (n=2), peritoneal thickening or nodules (n=1), lymphatic spread (n=1), intestinal wall thickening (n=1), and subcutaneous nodule (n=2). Isolated pelvis metastasis were found in 2.0% (95%CI 0.1%-3.9%, n=4) of all CT examination. The differences of incidence of pelvis metastases between patients with GC located in different stomach sites and between patients with enhanced CT and with non-enhanced CT were not significant (P=0.816, P=0.650, P=0.851). Conclusion In consideration of the limited yield of pelvic CT, health care cost, and radiation dose, the pelvic CT should not be performed routinely and should be reserved only for GC patients with suspected pelvic abnormalities.
【关键词】胃癌;肿瘤分期;盆腔;计算机断层扫描
【中图分类号】R735.2;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.11.030
前言
胃癌在全球恶性肿瘤发病率中名列第五位,是全球癌症的第三 大死因[1]。胃癌临床分期对于制定治疗方案及判断其预后具有重要的 指导意义[2]。目前世界上广泛使用的胃癌分期是由美国癌症联合会 (AJCC)和国际抗癌联盟(UICC)共同制定的TNM分期系统。CT在临床中 被常规应用于胃癌的分期,且通常包含胸部、腹部及盆腔[2]。然而, 国际指南中对于盆腔CT检查的推荐并不明确且无研究数据支持[2-5]。目 前医疗成本快速增长,常规或新开展的影像学检查通常须经严格审查 其价值及必要性[6]。据笔者所知,目前国内尚鲜见关于盆腔CT在胃癌 分期中价值及必要性的研究。故本研究回顾性分析在治疗前行全腹CT 检查(包含盆腔)胃腺癌患者的影像及临床资料,旨在评估盆腔CT在胃 腺癌分期中的价值与必要性及胃腺癌盆腔CT出现转移性病灶的相关因 素。
中国CT和MRI杂志
第16卷, 第 11 期
2018年11月
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