摘要
目的评估磁共振(MRI)及超声 心动图在慢性阻塞性肺疾病(COPD)患者 继发右心室功能不全中的诊断价值。方 法 遴选我院2017年2月至2018年2月确诊 为COPD且疑似继发右心室功能改变的118 例患者为研究对象,均采用MRI电影成像 法(Cine MRI)和实时三维超声心动图(RT3DE)检查,分析其影像图特点和右心功 能参数[射血分数(RVEF)、每搏输出量 (SVRV)、收缩末期容积(ESVRV)、舒张末 期容积(EDVRV)],评估两种检测方法的 一致性。结果 cine MRI检查示108例患者 右心室功能改变,影像学可见右肺动脉干 增粗,右心室扩大,室壁增厚,右心室肌 质量早期增加,晚期减弱,可见三尖瓣及 肺动脉瓣返流;RT-3DE检查示105例患者 右心室功能改变,影像学可见右心室内径 增大,室壁增厚,左心室受压,右心室流 出道内径增大,右肺动脉内径或肺动脉 干增大,还可见三尖瓣大量返流;cine MRI与RT-3DE测得的RVEF、SVRV、ESVRV、 EDVRV差异性不显著(P>0.05),两者评估 COPD患者继发右心室功能不全的一致率为 95.76%(Kappa=75.96%,P<0.05)。结论 cine MRI与RT-3DE都能较准确评估COPD患 者右心功能改变情况,二者评估一致性较 高,且影像检查图像具有一定的特征性, 均具有较高临床应用价值。
Objective To evaluate the diagnostic value of magnetic resonance imaging (MRI) and echocardiogram in secondary right ventricular dysfunction in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 118 patients diagnosed as COPD and suspected secondary right ventricular function changes from February 2017 to February 2018 in our hospital were enrolled in this study. All patients were given Cine magnetic resonance imaging (Cine MRI) and real-time threedimensional echocardiography (RT-3DE). The image features and right heart function parameters [right ventricular ejection fraction (RVEF), right ventricular stroke volume (SVRV), right ventricular end-systolic volume (ESVRV), right ventricular end-diastolic volume (EDVRV)] were analyzed, and the consistency of two detection methods was assessed. Results Cine MRI examination showed 108 cases of right ventricular function changes, and imaging showed thickening of right pulmonary artery, right ventricular enlargement, thickening of ventricle wall, early increase and late decrease of right ventricular muscle mass, and regurgitation of tricuspid and pulmonary valve. RT3DE examination showed 105 cases of right ventricular function changes, and imaging showed increase of right ventricular diameter, wall thickening, left ventricular pressure, increase of right ventricular outflow tract diameter, increase of right pulmonary artery diameter or pulmonary artery, and significant regurgitation of tricuspid. There was no significant differences in the RVEF, SVRV, ESVRV and EDVRV measured by Cine MRI and RT-3DE (P>0.05), and the consistency rate of the two methods for secondary right ventricular dysfunction in COPD patients was 95.76% (Kappa=75.96%, P<0.05). Conclusion Both Cine MRI and RT-3DE can accurately assess the changes of right heart function in patients with COPD. The two methods have high consistency in evaluation, and the imaging shows examination images have certain characteristics, and have high clinical application value.
【关键词】MRI;超声心动图;Cine MRI; RT-3DE;COPD;右心功能
【中图分类号】R541.5;R445.1;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.11.022
前言
慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)是常见的呼吸系统慢性疾病之一,具有高复发率、高发病率、高 死亡率和高致残率的特点,其临床典型特征为气流持续性受限,严重 影响患者正常呼吸功能[1]。COPD在40岁以上人群中的发病率高达10%, 是当前全球死亡原因的第4位,严重影响人民身体健康和生活质量[2]。 COPD患者晚期易并发慢性肺源性心脏病,导致肺动脉高压及右心室 肥大,最终发生右心功能改变,严重影响患者生命健康[3]。早期评估 COPD患者心功能改变,对于改善其预后意义重大,本次研究采用电影 磁共振成像法(Cine Magnetic Resonance Imaging,Cine MRI)和实时 三维超声心动图(real time three dimensional echocardiography, RT-3DE)两种影像学检查手段测量COPD继发右心室功能改变患者的右心 功能指标,旨在分析二者在COPD患者右心功能评估中的应用价值,从 而为COPD的临床防治提供科学依据。
中国CT和MRI杂志
第16卷, 第 11 期
2018年11月
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