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超声与MRI在诊断心肌梗死后左心室室壁瘤中的应用*

作者:张辉锋1 宋溢娟2 曲红培2 宋海乔3 陈瑞晓1

所属单位:1.河南科技大学第一附属医院心血管内科 2.河南科技大学第一附属医院心脏彩超室 3.河南科技大学第一附属医院磁共振室(河南 洛阳 471003)

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摘要

目的探讨超声和磁共振成像 (MRI)在诊断心肌梗死(CI)后左心室室壁 瘤(LVA)中的应用价值。方法 回顾性分 析2016年1月-2017年12月间收治的54例 疑为CI后LVA患者的临床资料,以病理检 查结果作为对照,患者均行超声心动图、 MRI和冠状动脉造影。比较超声与MRI检 测对CI后LVA的诊断应用价值,计算灵敏 度、特异度、准确率、阴性预测值和阳 性预测值。结果 ①超声心动图、MRI检 查LVA的检出率均为100%,诊断LVA分布 的准确率也均为100%,2组对比,差异无 统计学意义(P>0.05);②MRI矛盾运动区 域检出率明显较超声心动图高(P<0.05); ③MRI诊断CI后LVA后准确率高于超声检查 (P<0.05)。结论 超声与MRI在诊断CI后 LVA中均有其临床应用价值,应用MRI更有 利于鉴别诊断和判断LVA病情。

Objective To investigate the application value of ultrasound and magnetic resonance imaging (MRI) in the diagnosis of left ventricular aneurysm (LVA) after myocardial infarction (CI). Methods The clinical data of 54 patients with suspected LVA after CI between January 2016 and December 2017 were retrospectively analyzed. The results of pathological examination were used as controls, and the patients were given ultrasonic cardiogram, MRI and coronary angiography. The application value of ultrasound and MRI in the diagnosis of LVA after CI was compared, and the sensitivity, specificity, accuracy, negative predictive value and positive predictive value were calculated. Results The detection rates of LVA by ultrasonic cardiogram and MRI were 100%, and the accuracy rates in diagnosis of LVA distribution were also 100%, and there was no significant difference between the two groups (P>0.05). The detection rate of paradoxical movement area by MRI was significantly higher than that by ultrasonic cardiogram (P<0.05). The accuracy rate in diagnosis of LVA after CI by MRI was higher than that by ultrasound (P<0.05). Conclusion Both ultrasound and MRI have clinical application value in the diagnosis of LVA after CI. And MRI is more conducive to the differential diagnosis and judgment of LVA condition.

【关键词】超声;磁共振成像;心肌梗死后左心室室壁瘤;诊断

【中图分类号】R542.2+2

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.11.021

前言

心肌梗死(CI)发生后,梗死心肌局部变薄,运动幅度减弱或消 失,心肌应变能力下降,变性及坏死的心肌细胞逐渐被结缔组织取 代,坏死部位室壁向外膨出,形成室壁瘤,尤以左心室心尖部多 见[1]。左心室室壁瘤(LVA)形成后可导致左室舒张末期压力、室壁张力 及心肌耗氧量增加,左室扩张导致心力衰竭,继而影响患者心功能及 预后状况[2],因此LVA早期诊断、治疗对改善患者预后意义重大。冠状 动脉造影和是LVA诊断的常用方法,但作为一种有创检查存在较大限 制,且可导致左心室附壁血栓脱落。影像学诊断因其无创性、可重复 性等特点在临床应用广泛,近年来有学者指出磁共振成像(MRI)应用于 室壁瘤诊断也能发挥一定作用[3]。基于此,本研究回顾性分析54例疑 为CI后LVA患者的临床资料,以探究超声和MRI在诊断CI后LVA中的应用 价值,现报道如下。