摘要
目的探讨CT在甲状腺炎性结节 与甲状腺癌鉴别诊断中的价值。方法 收 集本院2012年3月至2017年10月间12例甲 状腺炎性结节及23例甲状腺癌病例,对两 类病变的形态、大小、边缘、位置、结节 内部情况、数目、钙化、周围间隙、淋巴 结肿大及密度、强化程度等进行分析及测 算,对比两种病变CT征象的差异性。结果 甲状腺炎多有弥漫性肿大,其结节边缘模 糊、多发、形态规则、少钙化或为粗大钙 化、少囊变、多累及峡部、颈部淋巴结肿 大不明显、多为强化均匀且延时强化。甲 状腺癌多为边界不清、形态不规则、单 发、细颗粒状或针尖样钙化、多见坏死囊 变、少累及峡部、颈部淋巴结肿大、密度 不均匀、明显不均匀强化,可见“咬饼 征”或“轮廓连线中断征”、“孤岛征” 等。甲状腺炎性结节与甲状腺癌病灶在年 龄、性别、边缘、病灶最大径没有明显 差别(P>0.05)。在病灶形态、数目、囊 变、钙化、峡部累及情况、颈部淋巴结肿 大方面及强化情况(均匀程度)等存在明显 不同,差异有统计学意义(P<0.05)。结 论 CT在甲状腺炎性结节与甲状腺癌鉴别 诊断中的有较高价值,值得在临床工作中 推广应用。
Objective To explore the value of CT in the differential diagnosis of inflammatory thyroid nodules and thyroid carcinoma. Methods A total of 12 cases of inflammatory thyroid nodules and 23 cases of thyroid cancer were collected between March 2012 and October 2017, and the morphology, size, edge, position, internal condition, number, calcification, peripheral clearance, lymph node enlargement and density and degree of enhancement of the two types of lesions were analyzed and measured, and the differences of CT manifestations of the two lesions were compared. Results Thyroiditis is more diffuse enlargement, the edge of the nodules are fuzzy, multiple, morphological rules and less calcified or for change, the more bulky calcification, less sac involving spondylolysis, cervical lymph node enlargement is not obvious, much as strengthening and delay strengthening. Thyroid cancer is boundary is not clear, form more irregular, single, fine granular or tip necrosis capsule calcification, see more, less involvement spondylolysis, neck lymph node enlargement, uneven density, strengthening the obvious and uneven, visible "bite of bread" or "contour connection interruption sign" and "islands", etc. Thyroid inflammatory nodules and thyroid cancer lesions were not significantly different in age, gender, edge, lesion maximum diameter(P>0.05). In lesions form, number, cystic change and calcification, isthmus, involvement and cervical lymph node enlargement and the enhancement (evenness) is obviously different, the difference was statistically significant (P<0.05). Conclusion CT has high value in the differential diagnosis of inflammatory thyroid nodules and thyroid carcinoma, and it is worth promoting the application in clinical practice.
【关键词】甲状腺癌;甲状腺炎;炎性结节;体层摄影术;X线计算机
【中图分类号】R736.1;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.11.012
前言
临床上甲状腺常见病变有三大类:炎症、增生及肿瘤病变,在此 类病变基础上产生的结节分别称为炎症性结节、结节性甲状腺肿及肿 瘤结节,其中肿瘤结节常见为甲状腺腺瘤及甲状腺癌。结节性甲状腺 肿、腺瘤及甲状腺癌的影像学表现在以往文献中有过不少报道,而甲 状腺炎性结节的影像学表现则较少有研究,并且甲状腺炎性病变的临 床及影像学表现与甲状腺癌有重叠,易误诊为甲状腺癌,故两者的鉴 别诊断显得很有必要,准确诊断则可以避免将炎性结节误诊为癌性病 变而进行不必要的手术切除治疗。本研究通过分析甲状腺炎性结节与 甲状腺癌的临床资料及影像学表现特点,以提高对此两种病变的CT诊 断与鉴别诊断水平,给临床诊治提供一定的指导作用。
中国CT和MRI杂志
第16卷, 第 11 期
2018年11月
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