摘要
目的总结分析头颈部及胸部髓 外浆细胞瘤影像学表现特点,提高对该 病的影像学诊断及鉴别诊断的能力。方 法 回顾性分析经病理证实6例髓外浆细胞 瘤病例影像学资料。结果 6例病例中,肿 块位于口咽部1例、鼻腔2例、肺内2例、 纵隔1例。CT表现为软组织密度肿块, 边界清楚,密度多均匀,增强扫描中等 度-明显强化,且肿瘤周边可见增粗血管 影;MRI表现为等或稍长T1,等或稍长T2信 号,DWI像扩散受限明显,部分病灶内可 见低信号分隔,肿瘤坏死不明显,增强扫 描明显均匀性强化。结论 髓外浆细胞瘤 具有一定的影像学特点,但缺乏特异性, 确诊需病理活检;术前CT及MRI检查能明 确病变范围、临近组织及淋巴结受累情 况,对该病的早期诊治、疗效评估有重要 意义。
Objective To summarize and analyze the imaging findings of extramedullary plasmacytoma(EMP) of the head , neck and thorax in order to improve the ability of imaging diagnosis and differential diagnosis of EMP. Methods A retrospective analysis was performed on imaging data of 6 patients with pathologically confirmed EMP. Results Of all the 6 cases included, 1 neoplasms was located in the oropharynx, 2 in the nasopharynx, 2 in the lungs and 1 in the mediastinum. CT demonstrated well-circumscribed, mildly or obviously enhancing soft tissue masses with dilated vessels around. MRI revealed isoor slightly long T1 and T2 signal intensity, with obviously restricted diffusion on DWI. Low-intensity septa was seen in some lesions and no remarkable necrosis was observed. Contrast-enhanced MRI showed homogenous enhancement of the masses. Conclusion EMP has several imaging features which are nonspecific and a definite diagnosis requires biopsy.Preoperative CT and MRI can help with the measurement of the extent of lesion and involvement of adjacent tissues and lymph nodes, which are of great significance for the early diagnosis and treatment evaluation of EMP.
【关键词】髓外浆细胞瘤;头颈部肿瘤; 胸部肿瘤;体层摄影术;磁共振成像;X线计算机
【中图分类号】R323.1;R826.63
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.11.010
前言
髓外浆细胞瘤(extramedullary plasmacytoma EMP)是指原发于骨 髓造血组织以外的浆细胞肿瘤(浆细胞瘤是一组疾病,包括多发性骨髓 瘤、孤立性浆细胞瘤和髓外浆细胞瘤[1-2]),是一种少见的由浆细胞构 成的软组织恶性肿瘤,约占所有浆细胞肿瘤的4%左右[3]。由于浆细胞 分布广泛,EMP可发生在任何有淋巴网状组织的器官,且80%分布于头 颈部[3],尤其以鼻腔、鼻窦及鼻咽部等上呼吸道多见[4-5],亦可见于中 枢、眼眶、甲状腺、纵膈等。由于EMP的治疗方案有别于其他类别肿 瘤,因此术前诊断尤为重要。本研究通过对经病理证实的4例髓外浆 细胞瘤病例的影像学表现进行分析总结,旨在提高对该病的影像学认 识。
中国CT和MRI杂志
第16卷, 第 11 期
2018年11月
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