论著-头颈部
双源CT双能量技术 在检测痛风患者四 肢关节尿酸盐沉积 中应用研究*
作者:柴瑞平1 张 红2 崔家梅3
所属单位:1.山东省滕州市中心人民医院影像 科 (山东 滕州 277500) 2.山东省滕州市人民医院影像中心 (山东 滕州 277500) 3.山东省滕州市荆河街道社区服务 中心 (山东 滕州 277500)
PDF摘要
目的 探讨双源CT双能量技术在 检测痛风患者四肢关节尿酸盐沉积中应 用价值。方法 选取2013年5月-2015年6 月我院收治的29例痛风患者(研究组)及 同期来我院体检的30例健康志愿者(对照 组)为研究对象,均行四肢关节双源CT双 能量扫描,并采用双能量CT物质分离法 处理图像,依据关节内有无尿酸盐沉积 将结果判定为阳性或阴性,对两组尿酸 盐沉积差异及双源CT检出尿酸盐沉积部 位进行观察比较。结果 双源CT双能量扫 描显示研究组尿酸盐结晶阳性率较对照 组高,差异有统计学意义(P<0.05);25 例临床诊断痛风结节患者均存在尿酸盐 结节沉积,4例临床初诊未发现痛风结节 而双源CT双能量检测出3例尿酸盐结晶沉 积,总检出率高达96.55%;双源双能量 CT检查对尿酸结节沉积病灶数目的检出 率明显高于临床查体。结论 双源CT双能 量技术在检测痛风患者四肢关节尿酸盐 沉积中具有较高应用价值,是诊断痛风 的有效手段,值得临床推广应用。
Objective To explore the application effect of dual source CT dual energy technique in the detection of extremities of gout patients. Methods A total of 29 gout patients (study group) treated in our hospital from May 2013 to June 2015 and 30 healthy volunteers (control group) in the same period were selected as the research objects, all research objects underwent dual source CT dual energy scanning in joints, dual energy CT decomposition method was used to process pictures, results were positive or negative according to whether there was uric acid salt deposits or not in joints of extremities, differences in uric acid salt deposits and uric acid salt deposits site detected by double source dual energy CT in the two groups were observed and compared. Results Positive rate of uric acid salt crystal examination after double source dual energy CT scanning in study group was significantly higher than control group (P<0.05). 25 cases of gout patients by dual energy CT scan showed urate deposition in the clinical diagnosis of nodules can be detected in patients with gout nodules, but in clinical examination of 4 patients found no gout nodules, but 3 were detected urate crystal deposited by dual energy CT scan, detection rate the detection rate is as high as 96.55%, examination diagnosed gout nodules significantly higher number of dual energy CT examination of the number of uric acid deposition nodules lesion. Conclusion Application effect of dual source CT dual energy technique in the detection of joints of extremities uric acid salt deposits in gout patients is high, and it is worthy of clinical application.
【关键词】痛风;双源CT;四肢关节; 尿酸盐沉积
【中图分类号】R593.21
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2017.12.041
前言
近年来,痛风发病率呈逐年上升趋势。痛风是一种代谢性疾病, 其形成与嘌呤代谢紊乱或尿酸排泄障碍、血尿酸增加从而引起机体 组织损伤有关,主要临床特征为反复发作急性关节炎、痛风石形成 等[1];其中高尿酸血症引发的尿酸盐晶体析出,同时在关节亦或结缔 组织中沉积而导致组织异物炎性反应是导致该病的关键因素[2]。目前 临床准确诊断痛风的方法较少,在以往的诊断中主要依据于血尿酸升 高和患者临床表现为主要依据,但仍有部分痛风发作的患者血尿酸水 平正常,故依据血尿酸水平高低诊断痛风不够准确[3]。随着影像学技 术水平不断上升,双源CT双能量扫描由于扫描过程中具有两种能量不 一的射线,对患者体内尿酸盐结晶有不同程度的能量衰减,因而在诊 断痛风方面具有一定价值[4],为进一步探讨双源CT双能量技术在检测 痛风患者四肢关节尿酸盐沉积中应用价值,笔者于本文展开临床对照 研究,结果简述如下。
中国CT和MRI杂志
第15卷, 第 12 期
2017年12月
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