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核磁共振(MRI)和CT 评估直肠癌术前T分 期的临床价值

作者:卫佳佳1 姬丽娟2

所属单位:1.河南省济源市人民医院磁共振室 (河南 济源 454650) 2.河南省焦作市人民医院 (河南 焦作 454150)

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摘要

目的 研究核磁共振技术(MRI)与 计算机断层摄影术(CT)评估直肠癌术前T 分期的临床价值。方法 选取我院2013年 3月至2016年3月62例直肠癌患者为研究对 象,所有患者均在我院行全直肠系膜切除 术,术前行MRI与CT检查。以术后组织病 理学结果为金标准,计算MRI与CT检查结 果诊断直肠癌T分期的灵敏度、特异度、 阳性预测值、阴性预测值、准确性。结果 与术后病理结果对照,MRI检查正确分期 52例,分期不足3例,分期过高7例,对直 肠癌T1期、T2期、T3期、T4期诊断符合率 分别为95.2%、90.3%、88.7%、93.5%,总 符合率83.9%,Kappa值0.746;CT检查正 确分期40例,分期不足8例,分期过高14 例,对直肠癌T1期、T2期、T3期、T4期诊 断符合率分别为91.9%、80.6%、72.6%、 83.9%,总符合率64.5%,Kappa值0.470。 MRI检查对直肠癌T3期及T分期总符合率显 著高于CT检查(P<0.05)。结论 MRI较CT 对直肠癌T分期诊断具有更高准确性,对 直肠癌治疗具有重要指导意义。

Objective To study the clinical value of magnetic resonance imaging (MRI) and computed tomography (CT) in evaluating the preoperative T stage of rectal cancer. Methods A total of 62 patients with rectal cancer treated in the hospital from March 2013 to March 2016were selected as subjects. All patients were treated by total mesorectal excision and were examined with MRI and CT before operation.The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MRI and CT findings in the diagnosis of T stage of rectal cancer were calculated with the histopathological results as the golden standard. Results Compared with postoperative pathology, MRI examination showed that the staging was correct in 52 cases, insufficient in 3 cases and too high in 7 cases. The diagnostic accordance rates of MRI for stage T1, T2, T3 and T4 of rectal cancer were 95.2%, 90.3%, 88.7% and 93.5%, respectively, and the total accordance rate was 83.9%, Kappa value was 0.746. CT examination showed that the staging was correct in 40 cases, insufficient in 8 cases and too high in 14 cases. The diagnostic accordance rates of MRI for stage T1, T2, T3 and T4 of rectal cancer were 91.9%, 80.6%, 72.6% and 83.9%, respectively, and the total accordance rate was 64.5%, Kappa value was 0.470. The accordance rate of MRI in the diagnosis of stage T3 and the total accordance rate in the diagnosis of T stage of rectal cancer were significantly higher than those of CT(P<0.05). Conclusion MRI is more accurate than CT in the diagnosis of T stage of rectal cancer, which is of important guiding significance for the treatment of rectal cancer.

【关键词】直肠癌;核磁共振技术;计算 机断层摄影术;分期

【中图分类号】R735.3+7

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2017.12.035

前言

直肠癌是消化道常见恶性肿瘤,随着人们生活方式改变,直肠癌 发病率与死亡率呈逐年上升趋势[1]。直肠癌治疗方案包括外科手术、 新辅助放疗、辅助化疗等,目前仍以根治性手术切除为主[2]。相关研 究显示,T1~2期患者接受根治性手术后,肿瘤复发率较低,可以有效 延长生存期,而T3~4期患者则无法直接从手术获益,需行术前辅助放 化疗,提高手术切除与根治率[3]。术前准确分期对直肠癌治疗方案选 择显得尤为重要,核磁共振技术(MRI)与计算机断层摄影术(CT)均为成 熟影像学技术,在直肠癌术前病理分期诊断中具有广泛应用。因此本 研究选取我院2013年3月至2016年3月62例直肠癌患者为研究对象,采 用MRI与CT检查,探讨MRI与CT评估直肠癌术前T分期的临床价值。