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螺旋CT和磁共振成 像检查进行直肠癌 术前肿瘤原发灶浸 润深度和淋巴结转 移准确性研究

作者:么 旺 滕 翀

所属单位:辽宁电力中心医院医学影像科 (辽宁 沈阳 110000)

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摘要

目的 利用螺旋 C T ( S p i r a l computed tomography, SCT)和磁共振成 像检查(Magnetic resonance imaging, MRI)进行直肠癌术前肿瘤原发灶浸润 深度(T)和淋巴结(N)分期,分析SCT和 MRI 在直肠癌术前分期诊断中准确性。 方法 本文对86 名经病理证实直肠癌患 者进行研究,其中46例术前行SCT检查, 40例术前行MRI检查。检查结果与术后病 理对照分析,比较两种方法对于直肠癌 术前分期准确性。结果 SCT对T分期总准 确度为:73.9%,术前SCT对T分期与病 理学对T分期一致性中等;对N分期总准 确度为:62.5%,灵敏度:87.5%,特异 度:68.2%,术前SCT 对N分期与病理学对 N 分期一致性中等。MRI对T分期总准确 度为:75.0%,术前MRI对T分期与病理学 对T分期一致性较好;对N分期总准确度 为:62.5%,灵敏度:85.7%,特异度: 61.5%,术前MRI对N分期与病理学对N分期 一致性中等。结论 MRI对直肠癌术前T 分 期诊断效能高于SCT;MRI及SCT对直肠癌 术前N 分期准确度均不理想。

Objective To analyze the staging accuracy of spiral computed tomography (SCT) and magnetic resonance imaging (MRI) in preoperative tumor (T) and lymph node (N) staging of rectal cancer in comparison with postoperative pathological staging. Methods Eighty-six patients with histologically proven rectal carcinoma. 46 of the 86 patients were staged preoperatively using SCT, and the other 40 patients using MRI. According to the compared results, we discussed and evaluated the accuracy of SCT and MRI for preoperative staging in rectal cancer. Results The overall accuracy of SCT for T staging was 73.9%. By statistical analysis we found that the correlation was middling between preoperative SCT and pathologic T staging. We determined the values for accuracy of SCT in N staging was 62.5%, for sensitivity 87.5%, and for specificity 68.2%. By statistical analysis we found that the correlation was middling between preoperative SCT and pathologic N staging. The overall accuracy of MRI for T staging was 75.0%. By statistical analysis we found that the correlation was good between preoperative MRI and pathologic T staging. The values for accuracy of MRI in N staging was 62.5%, for sensitivity 85.7%, and for specificity 61.5%. And by statistical analysis we found that the correlation was middling between preoperative MRI and pathologic N staging. Conclusion Both preoperative SCT and MRI scans could provide good predicts compared to subsequent pathologic T staging. Furthermore, the accuracy of MRI ismuch better than that of the SCT. Both preoperative SCT and MRI scans provided poor predictive data.

【关键词】直肠肿瘤;计算机断层成像; 磁共振成像;肿瘤分期

【中图分类号】R735.3+7

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.10.036

前言

CT和MRI方法是目前临床最常用于术前肿瘤分期另外两种影像学检 测方法[1]。CT扫描优点是其扫描范围能够覆盖整个腹腔和盆骨,因此 这种方法能够很清晰观察直肠癌细胞在肝脏中转移情况[2]。MRI是一种 非侵袭性检查手段,软组织分辨率高,并且可以从横断面、冠状面及 矢状面多方位成像,能清晰显示肿瘤与周围组织器官关系。这对直肠 癌术前分期评估有利[3]。临床分期往往用来指导首次治疗决策选择, 包括手术根治程度(根治或者保守)及手术方式选择以及是否推荐术前 治疗。因此,临床分期判断不准确,无论是临床分期过度或者分期不 足,都会对患者治疗造成明显影响[4-6]。本研究旨在比较此两种检查方 法在直肠癌术前分期方面准确度,从而为临床诊疗提供更为准确影像 学依据。