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结肠癌患者术前TNM分期、MSCT影像表现及病理表现特点分析*

作者:夏文骞

所属单位:山东省青岛市胶州中心医院CT室(山东 青岛 266300)

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摘要

目的 探讨结肠癌患者术前TNM分 期、多层螺旋CT扫描(MSCT)影像表现及病 理表现特点分析。方法 回顾性分析2009 年3月-2012年我院肿瘤外科收治的经手术 病理证实的40例结肠癌患者临床资料,病 例患者均行MSCT影像学检查,对所有病例 患者临床资料进行回顾性分析,以评估 MSCT影像技术在诊断结肠癌的应用价值。 结果 MSCT诊断结肠癌患者术前TNM分期 诊断准确例数为35例(87.50%),2例术前 T1-2期过低评估,术前病检为T3期、T4期 例数分别为1、1;且T3期中过低估计为 T1-2期、过高估计为T4期例数分别为0、 1;T4期中过低估计为T1-2、过低估计为 T3期例数分别为1、1,均差异有统计学意 义(P<0.001)。结肠癌MSCT影像学表现肠 壁不规则增厚,肠腔内外肿块,肠腔较狭 窄,增强CT扫描显示不同程度强化的肿 块,强化特点紧系于分化程度,而受侵部 位有浆膜和其邻近器官,浆膜面较毛糙亦 或周围脂肪层很模糊,有的甚至伴有浆膜 外索条影,表明周围脏器亦受侵,而区域 淋巴结转移,紧系于肿瘤病灶部位和相对 应的淋巴结回流,而肝脏是最为常见的远 处转移脏器。患者经术后组织病理检查提 示,腺癌、印戎细胞癌、管状腺癌、粘液 腺癌、乳头状腺癌、低分子型腺癌例数分 别为18、3、5、8、3、3。结论 MSCT对 结肠癌患者术前TNM分期有较好的评估价 值,有一定临床应用价值。

Objective To investigate the preoperative TNM staging, multi-slice spiral CT (MSCT) imaging findings and pathological features of patients with colon cancer. Methods The clinical data of 40 patients with colon cancer confirmed by surgery and pathology in our hospital between March 2009 and 2012 were retrospectively analyzed. MSCT was performed in all patients. The clinical data of all patients were analyzed retrospectively to evaluate the application value of MSCT imaging technology in the diagnosis of colon cancer. Results Thepreoperative TNM staging of patients with colon cancer was correctly diagnosed by MSCT in 35 cases(87.50%). For stage T1-2, there were 2 cases underestimated before operation. Pathological test showed that 1 case was stage T3 and 1 case was stage T4. There were 0 cases in stage T3 underestimated as stage T1-2 and 1 case overestimated as stage T4. In stage T4, there was 1 caseunderestimated as stage T1-2 and 1 caseunderestimated as stage T3. The diagnostic test consistency test showed Kappa=0.680(P<0.001). CT imaging findings of colon cancer showed intestinal wall thickened irregularly, masses inside and outside the lumen and relatively narrower intestinal cavity. Enhanced CT scanning showed masses with different degrees of enhancement, and the enhanced features was related to the degree of differentiation, while serosa and its adjacent organs were invaded. The serosal surface was coarse and surrounding fat layer was fuzzy, or with serosal stripped shadow, indicating that the surrounding organs were invaded, with regional lymph node metastasis, which was related to the location of tumor and reflux of the corresponding lymph nodes. Distal liver metastasis was common in organ metastasis. The postoperative pathological examination showed that Adenocarcinoma,signet ring cell carcinoma, tubular adenocarcinoma, mucinous adenocarcinoma, papillary adenocarcinoma, low molecular type adenocarcinoma cases were 18, 3, 5, 8, 3, 3. Conclusion MSCT is of good value in the evaluation of preoperative TNM staging of patients with colon cancer.

【关键词】结肠癌;MSCT;TNM分期;诊断

【中图分类号】R735.3+5

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.10.035

前言

结肠癌是目前临床常见、多发恶性肿瘤,近年来其发病率逐年上 涨[1],结肠癌患者早期无明显临床症状亦或临床症状较轻微,易被患 者及初诊医师忽视,而结肠癌患者出现典型症状及明确诊断时患者 早已处于中晚期,可见诊断不及时将严重延误患者疾病治疗,对患者 生命造成严重威胁[2]。目前,手术治疗仍是根治结肠癌的最佳手段, 因而术前对结肠癌患者病情进行准确评估对手术指征及手术方案制定 均有着重大意义;随着影像学技术水平不断提高,MSCT技术在诊断恶 性肿瘤病灶部位、肿瘤形态、肿瘤大小、病灶侵及范围等中的应用有 一定价值,因此已成为诊断结肠癌的主要手段[3]。为进一步探究MSCT 在结肠癌患者中诊断价值,笔者于本文展开回顾性分析,结果简述如 下。