简体中文

论著-头颈部

Askin瘤MSCT诊断及 误诊分析

作者:唐 琳1 刘书田1 周晓峰1 陈帅虎2

所属单位:1.湖南常德市第一人民医院放射科 (湖南 常德 415003) 2.中南大学湘雅医学院附属肿瘤医 院放射科 (湖南 长沙 410006)

PDF

摘要

目的 探讨Askin瘤的多层螺旋 CT特征及误诊原因。方法 回顾性收集 16例经病理证实的术前Askin瘤影像学资 料,总结分析Askin瘤的CT特征及误诊原 因。结果 16例Askin瘤患者发病年龄4.6 岁-32.4岁,中位年龄19.6岁;10例男 性,6例女性,16例患者均无石棉、粉尘等 有毒有害物质接触史。Askin瘤MSCT表现 多为胸肺交界区的不规则软组织肿块,14 例密度欠均匀,14例囊变,1例钙化,边 缘不清;增强扫描多呈中度以上不均匀明 显强化,周围结构侵犯15例,9例伴有少 量胸水;16例Askin瘤术前诊断正确5例, 误诊为恶性胸腺瘤6例,误诊为恶性胸膜 间皮瘤4例,误诊为周围型肺癌1例。结论 Askin瘤青年男性多见,无石棉、粉尘等 有毒有害物质接触史;MSCT表现为胸肺交 界区的不规则软组织肿块,呈弥漫性周围 侵润生长,囊变多见,钙化及邻近淋巴结 转移少见,有一定特征性;实际工作中需 要密切结合影像学及临床才能减少误诊。

Objective To discuss the imaging manifestations and misdiagnosis reason of askin tumor. Methods 16 cases of askin tumor confirmed by surgically and histopathologically were included in this study. Those MSCT signs and misdiagnosis reasons were summarized. Results 16 cases of askin tumor age from 4.6 to 32.4 years old, median patient age was 19.6 years old, including 10 males and 6 females. All the cases had no evidently history of exposure to asbestos. The imaging manifestations of askin tumor often occurred in the chest-lung junction region, inhomogeneous density, 1 case showed calcification, ill-defined, showed intense but inhomogeneous enhancement following contrast administration, 15 cases had the feature of adjacent structures involvement, 9 cases with little pleural effusion. Preoperative diagnosis was correct in 5 cases, 6 cases were misdiagnosed with thymoma, 4 cases were misdiagnosed with malignant pleural mesothelioma,1 case was misdiagnosed with peripheral lung cancer. Conclusion Askin tumor is easily occurred in young male without evidently history of exposure to asbestos; often show inhomogeneous density in the chest- lung junction region, with infiltration diffuse growth. Pleural effusions is very common, but common in calcification and adjacent lymph node metastasis. Combined with imaging and clinical is the key to reduce misdiagnosis in practical work.

【关键词】Askin瘤;体层摄影术;误诊

【中图分类号】R814.42

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.10.018

前言

Askin瘤是发生于胸部的外周性原始神经外胚层肿瘤(Peripheral Primitive Neuroectodermal Tumors,pPNET);其发病率非常低,临 床及影像学误诊非常常见[1]。以往的影像学研究,主要集中于Askin瘤 MSCT及临床诊断,且以个案报道为主[2]。本研究回顾性分析近14年来 我院经手术或穿刺病理证实的Askin瘤影像学征象,并对误诊原因进行 分析,提高对该病的影像学综合认识,减少误诊。