目的 探讨不同病理类型肺癌的 双源CT双能量参数特征及诊断鉴别价值。 方法 2010年1月1-2016年11月我院86例初 诊肺癌患者均接受双源CT双能量成像系统 检测，其中腺癌52例，鳞癌34例，扫描后 分析鳞癌、腺癌患者各期CT净增值和时 间-密度曲线，比较两组差异。结果 肺腺 癌主动脉达峰时间(21.04±0.23)s，肺鳞 癌(23.12±0.3)s，差异显著(P<0.05)； 增强扫描各期CT净增值比较，腺癌组在达 峰时、达峰后第60s、第100s显著高于鳞 癌组(P<0.05)；两组达峰后第40s差异不 具有统计学意义(P>0.05)；腺癌CT净增值 时间-密度曲线具有逐渐上升趋势特点， 而鳞癌时间—密度曲线具有先上升，后降 低，再平缓趋势。结论 双源CT双能量成 像可为腺癌、鳞癌病理学诊断提供一定参 考依据。

Objective To explore the dual-source CT dual-energy parameters and their value in differential diagnosis value of different pathological types of lung cancer. Methods A total of 86 cases of newly diagnosed lung cancer patients admitted to our hospital during November 2014 - November 2016 were examined with dual-source CT dual -energy imaging, including 52 cases of adenocarcinomas and 34 cases of squamous cell carcinomas. After scanning, the CT net added values and time-density curve of patients with squamous cell carcinoma and adenocarcinoma in different phases were analyzed and compared. Results The time to peak of was (21.04±0.23)s in the lung adenocarcinoma and (23.12±0.3)s in the lung squamous cell carcinoma, and the difference was significant(P<0.05). The CT net added values of enhanced scan in different phases in adenocarcinoma group to peak, 60s and 100s after reaching the peak were significantly higher than those of the squamous cell carcinoma group (P<0.05). There was no significant difference between the two groups at 40s after reaching the peak (P>0.05). The time-density curve of adenocarcinoma CT net added value shows a gradually increasing trend while that of squamous cell carcinoma shows an firstly increasing, then decreasing and finally flat trend. Conclusion Dual-source CT dual energy imaging can provide certain references for pathological diagnosis of adenocarcinoma and squamous cell carcinoma.