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原发性肝癌磁共振 与超声成像特点及 诊断价值分析

作者:古 今1 王 雨2 罗 丽3

所属单位:1.重庆市红十字会医院超声科 (重庆 400020) 2.重庆市肿瘤研究所/癌症中心影 像科 (重庆 400030) 3.重庆市肿瘤研究所/癌症中心超 声科 (重庆 400030)

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摘要

目的 比较分析原发性肝癌患者 磁共振(MRI)、超声成像特点及诊断价 值。方法 以本院2014年2月-2016年6月经 病理证实的73例原发性肝癌患者为研究对 象,对其MRI、超声影像学表现、诊断结 果相关资料进行回顾性分析。结果 MRI 确诊原发性肝癌70例,确诊率95.89%, 超声造影确诊原发性肝癌66例,确诊 率90.41%,常规超声确诊原发性肝癌56 例,确诊率76.71%,MRI、超声造影对原 发性肝癌确诊率均明显高于常规超声(P <0.05)。影像学表现方面,常规超声检 出肝胆管细胞癌2例,回声强弱不一,边 界模糊;早期肝癌17例,低密度病灶,边 界模糊;晚期肝癌37例,低回声,圆形、 类圆形状,边界清晰,病灶内血流丰富; 超声造影呈现“快进快出”特点50例; MRI平扫T1WI低信号,T2WI为不均匀高信 号,增强扫描显示不均匀强化。结论 超 声造影、MRI相比常规超声对原发性肝癌 确诊率明显高。

Objective To compare the characteristics and diagnostic value of magnetic resonance imaging (MRI) and ultrasound in patients with primary liver cancer. Methods 73 patients with primary liver cancer confirmed by pathology in our hospital between February 2014 and June 2016 were studied. The MRI and ultrasound imaging findings and diagnostic results were analyzed retrospectively. Results There were 70 cases with primary liver cancer confirmed by MRI, and the confirmed diagnosis rate was 95.89%. There were 66 cases with primary liver cancer confirmed by ultrasound contrast, and the confirmed diagnosis rate was 90.41%. There were 56 cases with primary liver cancer confirmed by routine ultrasound, and the confirmed diagnosis rate was 76.71%. The confirmed diagnosis rates of MRI and ultrasound contrast of primary liver cancer were significantly higher than that of routine ultrasound (P<0.05). Imaging findings showed that there were 2 cases with bile duct cell carcinoma detected by routine ultrasound detection, echo strength was different, and the boundaries were fuzzy, there were 17 cases with early liver cancer, with low-density lesions and fuzzy boundaries; there were 37 cases with advanced liver cancer, low echo, round or quasi-circular in shape, with clear boundaries, rich blood flow within lesions. Ultrasound contrast showed fast in fast out characteristics in 50 cases; MRI plain scan showed low signal on T1WI, and inhomogeneous high signal on T2WI. Enhanced scan showed inhomogeneous enhancement. Conclusion The confirmed diagnosis rates of ultrasound contrast and MRI in primary liver cancer are significantly higher than that of routine ultrasound.

【关键词】原发性肝癌;磁共振;超声; 成像特点

【中图分类号】R445;R735.7

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.12.024

前言

原发性肝癌(Primary hepatic carcinoma,PHC)包括肝细胞癌、 肝内胆管细胞癌等多种病理类型,具有发病隐匿、早期症状无特异 性、进展快等特点[1],临床确诊时大部分处于晚期或远处转移,增加 治疗难度,预后差[2]。为此早期诊断原发性肝癌对其及时治疗、预后 改善具有重要作用。目前临床诊断PHC方法较多,包括超声、CT、磁共 振成像(MRI)等,其中超声因其重复性强、无创、价格低等特点在PHC 早期筛查或诊断中比较常见,但超声检查易受患者体重、体位、仪器 性能等多种因素影响,对疾病定性难度大或易漏诊[3]。MRI检查具有分 辨率高、多参数成像等优点,能有效提高PHC诊断准确率。本研究对 2014年2月~2016年6月病理证实73例PHC患者超声、MRI影像学资料进 行回顾性分析,报道如下。