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CTA对诊断颅内动脉瘤的临床价值

作者:吴永刚 张 诚 黄啸元 杨小朋

所属单位:新疆维吾尔自治区人民医院神经外科(新疆 830001)

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摘要

目的 探讨CT血管造影(CTA)诊断 颅内动脉瘤的临床价值。方法 回顾性分 析2011年7月-2015年6月我院经手术及数 字减影血管造影术(DSA)确诊为颅内动 脉瘤的60例患者的临床资料,所有患者入 院后均接受CTA检查,与DSA结果对照, 分析CTA对颅内动脉瘤的诊断价值。结果 60例颅内动脉瘤患者经CTA检出73个动脉 瘤,其中单发43例,1例漏诊;15例多发 (30个),漏诊1例多发动脉瘤及多发动脉 瘤中瘤体直径较小的1个动脉瘤,CTA检出 颅内动脉瘤数目与DSA符合率为93.59%; CTA、DSA测定颅内瘤内动脉瘤最小径、 最大径及瘤颈宽度对比差异无统计学意义 (P>0.05);CTA不同重建方法中以VR重建 图像质量评分最高。结论 采用CTA诊断颅 内动脉瘤,无创,安全,价格低廉,图像 质量高,与DSA诊断准确率相近,临床应 用价值高,但对部分直径较小、CTA无法 明确诊断者,需配合DSA筛查。

Objective To investigate the clinical value of CT angiography (CTA) in the diagnosis of intracranial aneurysms. Methods The clinical data of 60 patients diagnosed with intracranial aneurysms by operation and digital subtraction angiography (DSA) in our hospital between July 2011 and June 2015 were retrospectively analyzed. All patients received CTA after admission, and the results were compared with those of DSA. The value of CTA in the diagnosis of intracranial aneurysms was analyzed. Results In 60 cases of patients with intracranial aneurysms, there were 73 aneurysms detected by CTA, including single ones in 43 cases and 1 case missed diagnosed; 15 cases of multiple ones (30). 1 case of multiple intracranial aneurysm and one aneurysm with relatively smaller diameter among multiple aneurysms were missed diagnosed. The coincidence rate of CTA in detecting the number of intracranial aneurysms with DSA was 93.59%; There were no significant differences between CTA and DSA in the determination of the minimum diameter, maximum diameter and aneurismal width of intracranial aneurysms (P>0.05). Among different reconstruction methods of CTA, the image quality score of VR reconstruction was the highest. Conclusion CT angiography in the diagnosis of intracranial aneurysm is noninvasive, safe and inexpensive, with high quality image. The diagnostic accuracy is similar to that of DSA, and the clinical application value is high. However, for some patients with aneurysms of which the diameter is relatively smaller and patients who cannot be diagnosed by CTA, DSA screening should be carried out.

【关键词】颅内动脉瘤;CT血管造影; DSA;诊断

【中图分类号】R445.3;R743

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.09.009

前言

颅内动脉瘤系局部血管异常改变所致脑血管瘤样凸起,为常见颅 内脑血管病,是引起自发性蛛网膜下腔出血(SAH)的重要原因[1]。一般 颅内动脉瘤患者早期无特异性表现,在颅内动脉瘤破裂出血前较难检 出,导致治疗延误,影响患者预后。DSA是诊断颅内动脉瘤的传统方 案,但其耗时长,价格昂贵,且为有创性操作,有其并发症,患者可 接受度低[2]。而CTA血管造影则为无创性血管造影技术,有其较高的时 间、空间分辨率,配合三维重建处理,可清晰显示病变形态特点,明 确其与周围血管解剖关系,且检查耗时短,层厚薄,扫描速度快,目 前已广泛应用于脑血管病的临床筛查[3]。为探讨CTA诊断颅内动脉瘤临 床价值,我院对收治的60例颅内动脉瘤患者的临床资料进行了回顾性 分析,现报道如下。