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论著-头颈部

真菌性鼻窦炎患者CT与MRI诊断分析

作者:刘红生1,2 杨军乐1,2 邬小平2 马鸣岳2 赵芸芸2

所属单位:1.西安交通大学医学院 (陕西 西安 710061) 2.西安交通大学医学院附属西安 市中心医院放射科 (陕西 西安 710003)

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摘要

目的 分析CT与MRI诊断真菌性鼻 窦炎的临床价值。方法 回顾性分析2011 年6月-2015年5月于我院经病理证实为真 菌性鼻窦炎的32例患者的临床资料,所有 患者入院后均接受CT与MRI检查,总结其 影像学特点,分析CT、MRI对真菌性鼻窦 炎的诊断价值。结果 CT:32例中,上颌 窦发病16例,右侧9例,左侧7例;9例蝶 窦受累,筛窦7例。表现为窦腔内密度不 均软组织影,软组织窗显示非规则窦腔内 钙化,受累窦壁骨质可见增生硬化,窦周 边界清晰;MRI:与脑实质比较,7例T1WI 序列呈均匀低信号,21例等信号,4例伴 少量低信号;T2WI病变以低信号为主,伴 形态、数量不一高信号;受累鼻窦阻塞性 炎症T2WI序列呈高信号,T1WI序列呈等信 号,边缘伴明显强化。可侵犯眼眶、海绵 窦、脑实质、侵犯颞下窝、翼腭窝,部分 可见鼻咽部软组织增厚,可伴硬腭骨质破 坏。结论 在真菌性鼻窦炎诊断中,CT对 钙化灶显示率高,可作为首选检查方法, 而MRI在显示病变窦腔受累方面优势更 佳。

Objective To analyze clinical value of CT and MRI in the diagnosis of fungal sinusitis. Methods A retrospective analysis from June 6, 2011-May 2015 in our hospital conducted by pathology for the clinical data of 32 cases with fungal sinusitis. All patients were examined by CT and MRI after admission. The authors summarized their imaging characteristics and analyzed the CT and MRI in the diagnosis of fungal sinusitis. Results CT: 32 cases of maxillary sinus disease in 16 cases, 9 cases on the right side, 7 cases on the left side, 9 cases of sphenoid sinus involvement, and 7 cases of ethmoid sinus. Uneven density of soft tissue were visible in the sinus cavity, soft tissue window showed irregular calcifications in sinus cavity, the affected sinus wall displayed bone hyperplasia and sclerosis, the paranasal sinus boundary was clear. MRI: Compared with brain parenchymal, 7 cases of T1WI showed low signal intensity, 21 cases showed equal signals, while 4 cases showed small amount of low signals. Lesions with the priority of low signals, together with few high signals of different forms and amount on T2WI, the affected sinus had obstructive inflammation that showed high signal on T2WI , while the T1WI sequence had equal signals with the obvious peripheral enhancement. Lesions could be invasive to orbit, cavernous sinus, brain parenchyma, infratetemporal fossa and pterygopalatine fossa, and the nasopharyngeal soft tissue had been thickened obviously together with the destruction of hard palate. Conclusion In the diagnosis of fungal sinusitis, the successful rate from CT for calcifications checking is higher. It can be used as the preferred examination method, and the advantage of magnetic resonance imaging (MRI) in the sinus cavity involvement is even better.

【关键词】鼻窦炎;真菌性;体层摄影; 磁共振成像

【中图分类号】R765.4+1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.09.003

前言

真菌性鼻窦炎是较罕见鼻窦炎类型,由鼻窦特殊致病菌感染所 致。目前随抗生素、免疫抑制剂、类固醇的广泛使用与环境污染的加 重,真菌性鼻窦炎发病率有所上升。且真菌性鼻窦炎患者通常无特异 性症状表现,与鼻窦肿瘤、慢性鼻窦炎鉴别困难。以往对真菌性鼻 窦炎的诊断多赖于组织病理学诊断,但其为有创性操作,可接受度 差[1]。近年来,随着影像学技术的进步,真菌性鼻窦炎术前检出率不 断提高。有研究者[2]表示,CT对气腔结构显示率好,同时可清晰显示 鼻窦炎病变部位、骨质改变等。也有观点[3]表示,MRI可明确病灶侵袭 范围,对海绵窦、脑实质、眶尖部分病变显示良好。基于此,为进一 步探讨CT、MRI在真菌性鼻窦炎诊断中的应用价值,我院对收治的32例 患者的临床及影像学资料进行了回顾性分析,现报道如下。