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胸腺瘤CT影像学特点与病理的关系分析

作者:杨志惠

所属单位:凉山彝族自治州第一人民医院(四川 西昌 615000)

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摘要

目的 探讨胸腺瘤CT表现及其 与病理的关系。方法 对本院2014年1 月-2016年1月就诊64例胸腺瘤患者CT影像 学及临床病理资料进行回顾性分析,观察 胸腺瘤CT表现,并分析CT与病理分型、分 期的关系。结果 CT表现:平扫显示胸腺 瘤病灶均在前纵隔部位;不规则形态占 79.69%;密度不均占68.75%;增强扫描显 示明显强化46例;胸膜侵犯25例,肺结 节、纵隔淋巴结肿大各5例。良性(A型与 AB型)、恶性(B型与C型)胸腺瘤在肿块形 态、边缘、密度、强化程度、局部侵犯及 转移方面差异显著(P<0.05)。胸腺瘤CT 分期与病理分期比较差异无统计学意义(P >0.05);CT分期I-II期中A型、AB型24 例,III-IV期中B型、C型27例。结论 病 理A型、AB型与B型、C型胸腺瘤CT表现存 在较大的差异,CT影像学表现对胸腺瘤良 恶性(病理分型)及临床分期判断有重大价 值,能为胸腺瘤临床诊治、预后评估提供 重要依据。

Objective To explore thymoma CT imaging features and its relationship with pathology. Methods Arestrospective analysis of CT imaging and clinicopathological data was carried out in 64 patients with thymoma treated in our hospital from January 2014 to January 2016,thymoma CT features were observed, relationship between CT, pathological type and stage were analyzed. Results CT features: plain scan showed that thymoma lesions existed in mediastinum anterius part, irregular shapes accounted for 79.69%, uneven densities accounted for 68.75%, enhancement scanning showed obvious enhancement existed in 46 cases, pleural invasion existed in 25 cases, pulmonary nodule existed in 5 cases, mediastinal lymph node enlargement existed in 5 cases. There was a significant difference in tumor shape, edge, density, strengthening degree, local invasion and metastasis of benign (type A and type AB) and malignant (type B and type C) thymomas (P<0.05). There was no significant difference in thymoma CT staging and pathological staging (P>0.05), there were 24 cases of type A, type AB in CT stage I -II stage, 27 cases of type B, type C in III-IV stage. Conclusion There is a significant difference in pathological type A, type AB and type B, type C thymoma CT features,CT imaging features has great value in thymoma benign and malignant (pathological type) and clinical staging judgement, can provide an important basis for clinical diagnosis and prognosis evaluation of thymoma.

【关键词】胸腺瘤;CT;影像学表现;病 理分型;关系

【中图分类号】R445.3;R736.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.09.019

前言

胸腺瘤在前纵膈肿瘤中比较常见,占1/2左右,好发于成年人群, 且多数患者临床就诊时处于癌症状态,预后较差。根据性质胸腺瘤主 要分为良性与恶性肿瘤(包括侵袭性胸腺瘤及胸腺癌),不同性质胸腺 瘤治疗方案及预后存在较大的差异[1],而临床上世界卫生组织(WHO) 病理分型、分期在很大程度上直接关系到胸腺瘤CT影像学表现及预 后[2]。近年来CT在胸腺瘤诊断中发挥重要作用[3],但关于胸腺瘤CT影 像学表现与其临床病理相关性报道还不是很多,基于此,本研究回顾 性分析2014年1月~2016年1月就诊64例胸腺瘤患者CT影像学及临床病 理资料,分析两者之间的关系,以为临床胸腺瘤诊治提供重要依据。 报告如下。