目的探讨颈动脉粥样硬化患者 应用瑞舒伐他汀药物对血气指标与颈动脉 斑块的影响。方法 选择我院60例经颈动 脉多普勒超声检查证实有颈动脉斑块患者 为研究对象，将其分为对照组与观察组， 对照组患者给予肠溶阿司匹林治疗，观察 组患者给予瑞舒伐他汀及肠溶阿司匹林治 疗，比较两组患者的治疗效果、血气指标 与颈动脉斑块的影响。结果 观察组治疗 后三酰甘油、高密度脂蛋白胆固醇水平、 斑块数量与对照组相比，没有明显差异， p＞0.05；观察组治疗后总胆固醇、低密 度脂蛋白胆固醇、斑块厚度明显优于对照 组，p＜0.05，差异具有统计学意义。结 论 颈动脉粥样硬化患者应用瑞舒伐他汀 药物可以有效降低患者血清中的总胆固醇 以及低密度脂蛋白胆固醇，降低患者斑块 的厚度，具有较高的临床使用价值。

Objective To explore effects of Rosuvastatin on the vigor index and carotid plaques of patients with carotid atherosclerosis. Methods Sixty patients with carotid atherosclerosis of carotid plaques which confirmed by carotid artery Doppler ultrasonography were admitted as research subjects, and the patients were divided into the control group and the observation group, patients in the control group were subject to enteric coated Aspirin treatment, and patients in the observation group were subject to Rosuvastatin combining enteric coated Aspirin treatment, efficacies and corresponding affects on the vigor index and carotid plaques of patients in two groups were compared. Results There was no difference in the level of triacylglycerol, high-density lipoprotein cholesterol and number of patches of patients between the observation group and control group after the treatment (p>0.05). The total cholesterol, low-density lipoprotein cholesterol and plaque thickness of patients in the control group were better than that in the control group (p<0.05), and the difference was statistically significant. Conclusions Rosuvastatin applied on patients with carotid atherosclerosis is capable of reducing the serum total cholesterol and low density lipoprotein cholesterol, decreasing the thickness of the plaques and improving the life quality of patients, which deliver high value in clinical.