论著-头颈部
探讨骨样骨瘤影像学特点及冷循环射频消融对其治疗效果评估
作者:涂恒业1 席 强2 赵 鑫2 冀 鑫2
所属单位:1.河北北方学院附属第一医院放射科(河北 张家口 075000) 2.河北北方学院附属第一医院放疗科(河北 张家口 075000)
PDF摘要
目的研究髓内骨样骨瘤影像特 点,探讨磁共振在评估冷循环射频消融治 疗效果的应用价值。方法 3例进行冷循环 射频消融术髓内骨样骨瘤,48例行非冷 循环射频消融术的皮质和骨膜下骨样骨瘤 患者,术后观察比较两组影像学变化。结 果 髓内骨样骨瘤X线、CT瘤巢周围软组织 及骨髓肿胀明显,边界不清晰,瘤巢不 典型,部分无周围硬化缘。MRI可查到瘤 巢,髓内呈软组织信号改变,可表现为假 象侵袭性表现。术后所有患者疼痛缓解和 临床症状改善。骨样骨瘤患者中,治疗后 24月随访后,无复发现象。28例骨皮质和 骨膜下型需补加非冷循环射频消融术。3 例髓内骨样骨瘤术后完全治愈。结论 CT 引导的RFTA 将成为儿童第一线治疗方 法,因创伤性低,并发症率少。应用冷态 模型,骨样骨瘤局部治疗是非常有效的。 治疗成功指标是疼痛消失和MR图像骨髓信 号恢复正常。
Objective To study the particular imaging features of intramedullary osteoid osteoma and evaluate success rate of cold mode radio-frequency thermal ablation (RFTA) as the treatment of it. Methods Three patients had tibial intramedullary osteoid osteoma who underwent RFTA and forty-eight patients with cortical and subperiosteal lesions were treated by the non-cooled mode, finally compared the difference between the two groups. Results The swelling of marrow and the soft tissue around the nest, no Clear boundary, the nest is not typical, no hardening around the rim with intramedullary osteoid osteoma. The intramedullary soft tissue changes may show as a misleadingly aggressive appearance in MRI. Treated by the RFTA, all patients were pain-free and in good recovery. In the intramedullary osteoid osteoma group, no recurrences were observed during the 24-month follow-up period, but 28 patients who got cortical osteoid osteoma required a supplementary RF treatment to completely heal the lesion. Three patients had complete healing by the RFTA. Conclusion CT-guided RFTA should be the first treatment for intramedullary osteoid osteomas because of the high success rate and its reduced invasion. With cold-mode RFTA. The outcome is promising. The success indicators for treatment are the disappearance of pain and the absence of lesion in the ablation area detected by MRI.
【关键词】骨样骨瘤;射频消融;磁共振成像;计算机体层摄影术
【中图分类号】R445.2;R445.3;R738.1
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2015.08.030
前言
髓内骨样骨瘤一种相对少见病,国内外报道研究较少。骨样骨瘤 很少不显示瘤巢和无骨膜反应,其髓内骨样骨瘤影像学表现特点不同 于常见皮质型骨样骨瘤,也不显示病变硬化边缘[1]。手术是治疗骨样 骨瘤主要治疗手段,但创伤性大,术后入路困难,术后并发症较多。 近十年来,相关文献报道应用环钻术注射乙醇、冷冻消融术、激光凝 固法等创伤性较小治疗方法[2]。近期,CT引导下经皮射频热消融证实 创伤性小,治疗成功路高。相关文献报道射频热消融是治疗四肢骨及 骨盆骨样骨瘤最佳治疗方法,另一些学者认为年龄较小患者射频热消 融容易治疗失败,但也有学者认为年龄小与治疗是否成功无统计学差 异[3]。目前为止,较少文献报道冷循环射频热消融治疗儿童髓内骨样 骨瘤,认为经皮冷循环射频热消融创伤小,对治疗儿童髓内骨样骨瘤 安全性和有效性较高。本研究目的是探讨髓内骨样骨瘤影像学特点及 评估冷态射频热消融治疗骨样骨瘤的效果。
中国CT和MRI杂志
第13卷, 第 8 期
2015年08月
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