目的探讨磁敏感加权成像(SWI) 在帕金森病(PD)及血管性帕金森综合征 (VP)诊断、鉴别诊断中的临床应用价值。 方法 收集我院2013年6月-2015年3月间 收治的30例帕金森病患者(PD组)及25例 血管性帕金森病患者(VP组)，同时将同 期收集25例健康老年人(NC组)纳入对照 组。三组患者均行磁敏感加权成像检查， 比较三组患者黑质致密带(SNc)、黑质网 状带(SNr)、红核(RN)、苍白球(GP)、 壳核(PUT)和尾状核(CN)中的相位值。 结果 PD组中黑质致密带(SNc)、苍白球 (GP)、壳核(PUT)的相位值明显低于VP组 (P<0.05),两组黑质网状带(SNr)、红核 (RN)和尾状核(CN)的相位值比较无明显差 别(P>0.05)，VP组中各核团相位值与NC组 相比无明显差别(P>0.05)。结论 运用磁 敏感加权成像测定PD及VP患者黑质致密 带、苍白球、壳核中的相位值对二者诊 断、鉴别诊断起到一些参考价值。

Objective To investigate the susceptibility weighted imaging (SWI) in Parkinson's disease (PD) and vascular vascular parkinsonism (VP) diagnosis, differential diagnosis of clinical value. Methods Collected in our hospital in June 2013-March 2015 30 cases were treated with Parkinson's disease (PD group) and 25 cases of patients with vascular parkinsonism (VP group), while 25 cases of healthy elderly will collect the same period (NC group) included in the control group. Three patients underwent magnetic resonance susceptibility weighted imaging compared three groups of patients in the substantia nigra pars compacta (SNc), substantia nigra pars reticulata band (SNr), red nucleus (RN), globus pallidus (GP), putamen (phase value PUT) and the caudate nucleus (CN) in. Results PD group in the substantia nigra pars compacta (SNc), globus pallidus (GP), putamen (PUT) phase was significantly lower than VP group (P<0.05),, red nucleus with two substantia nigra pars reticulata (SNr) (RN) and the caudate nucleus (CN) phase value was no significant difference (P>0.05), VP group phase value of each nuclei compared with the NC group had no significant difference (P>0.05). Conclusion Measured using susceptibility weighted imaging in patients with PD and VP with substantia nigra, globus pallidus, putamen phase values for both diagnosis and differential diagnosis play some reference value.