摘要
目的利用临床疑诊为急性肺动 脉栓塞患者CTPA的检测资料,评价患者心 室大小并与经胸超声心动图(TTE)检查结 果进行一致性和相关性分析,探讨CTPA在 右心室功能评价的可行性和准确性。方 法 选取90例疑诊为肺动脉栓塞患者,其 中50例患者于CTPA检查前后1d内行TTE检 查。所有患者均使用128排螺旋CT行CTPA 检查。采用二维测量方式评价心室大小: 横断位心室内径(LVtrans、RVtrans);重建四腔 心位心室内径(LV4ch、RVtrans)及计算得出的 相应心室参数比值(RV/LVtrans、RV/LV4ch)。 使用相应参数在TTE图像上评价心室大 小:舒张末期左心室内径(LVTTE)、舒张末 期右心室内径(RVTTE)以及计算得出的心 室内径比值(RV/LVTTE)。利用上述数据评 价CTPA与TTE结果的一致性和相关性。结 果 RVtrans与RVTTE无显著相关性(P>0.05), LVtrans与LVTTE正相关(r=0.56,P<0.01)。 RV4ch与RVTTE正相关(r=0.37,P<0.01)。 LV4ch与LVTTE正相关(r=0.48,P<0.01)。 CTPA与TEE测得心室直径间具有统计学差 异(P<0.01,P<0.05)。RV/LV4ch、RV/LVtrans 与RV/LVTTE做相关分析,显示相关不密切 (P>0.05),组间直径比值间具有显著差异 (P<0.01)。结论 CTPA是评价心室大小的 简单方法,与TTE实际测量值具有一定的 相关性和一致性。二维内径值之间具有较 好的一致性和相关性,但二维比值间相关 性不显著。CTPA容积比值与TTE二维比值 无相关,但具有较好一致性。
Objective Using detection data of clinically suspected CTPA patients with acute pulmonary embolism, evaluation of patients with ventricular size and transthoracic echocardiography Beckoning diagram (TTE) to check the results of the analysis of consistency and correlation, to explore the feasibility and accuracy of CTPA in the evaluation of right Hventricular function. Methods 90 cases of patients with suspected pulmonary embolism, among them 50 patients received TTE examination before and after CTPA examination 1D. All patients were using 128 slice spiral CT for CTPA examination. Using a two-dimensional measurement evaluation of ventricular size: axial ventricular diameter (LVtrans, RVtrans); reconstruction of four chamber a ventricular diameter (LV4ch, RVtrans) and calculated the corresponding ventricular parameters (RV/LVtrans, RV/ LV4ch) ratio. The assessment of ventricular size in TTE image using the corresponding parameters: end diastolic left ventricular internal diameter (LVTTE), end diastolic diameter of right ventricle (RVTTE) and the calculated ventricular diameter ratio (RV/LVTTE). Consistency and correlation by using the above data evaluation of CTPA and TTE results. Results RVtrans and RVTTE showed no significant correlation (P>0.05), LVtrans is positively correlated with LVTTE (r=0.56, P<0.01). RV4ch was positive correlation with RVTTE (r=0.37, P<0.01). LV4ch was positive correlation with LVTTE (r=0.48, P<0.01). CTPA and TEE measured with statistical difference between ventricular diameter (P<0.01, P<0.05). RV/LV4ch, RV/LVtrans and RV/LVTTE correlation analysis, shows no direct correlation between the groups (P>0.05), with significant difference between the diameter ratio (P<0.01). Conclusion CTPA is a simple method for evaluation of ventricular size, and the actual measured value with TTE and consistent correlation. The value of two-dimensional in between with consistency and better correlation. But no significant correlation between two-dimensional ratio. CTPA volume ratio and TTE ratio had no correlation with 2D, but the better consistency.
【关键词】急性肺栓塞;肺动脉造影;心功能评估
【中图分类号】R563.5;R814.42;R814.43
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.08.011
前言
肺动脉栓塞(PE)是一种严重的心血管疾病,具有潜在的致死性, 也是心跳骤停的原因之一,其发病率和病死率居第3位[1,2]。PE对于患 者健康的威胁主要来自于疾病对肺循环的影响,当肺血管床的阻塞大 于35%时右心房压升高,而当大于50%时,可导致肺动脉压和肺血管阻 力显著增加,因此而发生的右心室功能不全会严重影响患者的预后 [3,4]。因此,对于心功能的监控是PE患者的监测重点。经胸超声心动图 (TTE)是最为常用的超声心动图,其优势在于无侵入性操作和无对比剂 应用,然而除非探头探及肺动脉栓塞否则无法诊断PE[5,12]。多层螺旋 CT肺动脉造影(CTPA)是诊断PE的有效方法[13],探讨CTPA与TTE结果的一 致性和相关关系,对于寻找简单可靠的检测PE患者心功能的方法,具 有重要意义。
中国CT和MRI杂志
第13卷, 第 8 期
2015年08月
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