摘要
目的探讨与分析CT应用于胰腺 癌与自身免疫性胰腺炎的鉴别价值。方 法 选取我院所收治的16例胰腺癌和16例 自身免疫性胰腺炎患者分别采用CT检查, 比较2者胰腺肿胀或局灶性密度减低及强 化方式、被膜样边缘、血管受侵犯、钙 化、假囊肿形成、胰管改变、肾脏受累情 况。结果 2组胰腺肿胀和局灶性密度减低 及弥漫性强化减低、被膜样边缘、血管受 侵犯、胰管截断、肾脏受累存在明显差异 性(P<0.05)。结论 临床采用CT用于诊断 胰腺癌与自身免疫性胰腺炎可提供准确信 息,进而为临床鉴别提高重要参考价值。
Objective To discuss and analyze the application value of CT in the differential diagnosis of pancreatic cancer and autoimmune pancreatitis. Methods 16 cases with pancreatic cancer and 16 cases with autoimmune pancreatitis were performed with CT in our hospital. The pancreatic edema or focal decreasing of density and enhancement pattern, the edge, vascular invasion, calcification, pseudocyst formation, pancreatic duct changes and renal involvement were compared between the two groups. Results The differences of pancreatic edema or focal decreasing of density and enhancement pattern, the edge, vascular invasion, pancreatic duct changes and renal involvement between the two groups had statistical significance (P<0.05). Conclusion The clinical use of CT for the differential diagnosis of pancreatic cancer and autoimmune pancreatitis could provide accurate information and has important value for clinics.
【关键词】CT;自身免疫性胰腺炎;胰腺癌
【中图分类号】R735.9
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.04.23
前言
临床上自身免疫性胰腺炎主要是胰腺对自身成分作为抗原由CD4阳 性的辅助细胞识别产生免疫应答的结果,最终导致胰腺发生炎症性病 变[1]。自身免疫性胰腺炎临床病理学主要表现为胰腺明显淋巴细胞浸 润,并伴胰腺纤维化,进而导致胰腺功能发生障碍,其主要分为胰管 狭窄型慢性胰腺炎和局限性胰管狭窄型慢性胰腺炎[2]。而局限性胰管 狭窄型慢性胰腺炎与胰腺癌的鉴别诊断成为临床影像学的难题,且两 者治疗方法存在明显差异。因此为提高临床诊断率,同时为临床治疗 方案正确选择提供参考依据,本次研究采用CT用于诊断自身免疫性胰 腺炎与胰腺癌中,以探讨其临床鉴别诊断价值,报道如下。
中国CT和MRI杂志
第13卷, 第 4 期
2015年04月
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