目的探讨颅内原发中枢神经系 统淋巴瘤(PCNL)的影像学特点。资料与方 法 回顾性分析14例经病理证实的PCNL的 CT、MR及MRS及表现。结果 PCNSL影像学 特点如下：1.好发于深部脑组织，如额 叶、胼胝体及基底节区。2.病灶CT上表现 为等、高密度，瘤周水肿呈轻中度。3.MR 上T1呈等、低信号，T2呈等、稍低信号， 边界清楚。4.增强呈均匀明显强化，特征 性的表现包括“缺口征”、“蝶翼征” 等。5.在1 H-MRS上，PCNSL特征性的表现 为高耸的Lip峰，且其常表现为胆碱(Cho) 峰升高、肌酸(Cr)峰降低，氮-乙酰天冬 氨酸(NAA)缺失。结论 PCNSL的CT、MR表 现多样，具有一定的特征性表现，1 H-MRS 可以帮助提高PCNSL正确的诊断率。

Objective To discuss imaging features of primary central nervous system lymphoma. Methods CT、MR and MRS findings of 14 patients with pathologically proved PCNSL were analyzed retrospectively. Results Imaging feature of PCNSL were as follows: (1) the most common site of involvement was deep brain tissue like the frontal lobes, the corpus callosum and the basal ganglia; (2) high or isodense on CT images, slightly edema around the lesions; (3) high density or isodense on T1-weighted images and isodense or slight high density on T2-weighted images; well-defined; (4) enhancement was obvious and homogeneous; the presence of "incision sign" and "butterfly sign" were more specific. Conclusion Imaging of CT and MR of PCNSL was varied, but has some features. 1 H-MRS could help the diagnosis of PCNSL.