目的探讨多层螺旋CT(MSCT) 定量指标对肺减容术 ( l u n g v o l u m e reduction surgery, LVRS)患者肺形态 及功能预测的应用价值。方法 16例行 LVRS患者，术前一周完成CT和肺功能试 验(PFT)，出院前至术后6个月复查CT和 PFT。MSCT采用深吸气末扫描全肺，后处 理工作站中定量测定肺密度、全肺功能 性肺容积、预保留肺的功能性肺容积、 拟手术“靶区”容积等形态学指标。应 用术前CT 测定的容积数据与PFT测得的 FEV1.0%、FEV1.0/FVC计算术后预测值， 将预测值与术后PFT实测值行相关性分 析。结果 预测值与术后PFT实测值有良好 的相关性。结论 MSCT能直观、定量评估 LVRS病变的范围、程度、类型等形态学信 息，并能良好预测术后肺功能。

Objective To study the application value of MSCT in the prediction of lung morphology and lung function in the patients with lung volume reduction surgery. Methods 16 patients with LVRS underwent CT and pulmonary function test (PFT) a week before surgery, and reexamined CT and PFT in 6 months after the surgery. The whole lung was scanned in the end of deep inspiration, and the lung density, total lung functional volume, preserved lung functional volume and proposed surgical target area volume were quantitatively measured in the post-processing workstation. Postoperative predicted value was calculated according to the preoperative volume data measured by CT and FEV1.0% and FEV1.0/FVC measured by PFT, and the correlations between predicated value and postoperative data was analyzed. Results The predicted values and the postoperative PFT measured values have good correlation. Conclusion MSCT can intuitively and quantitatively evaluate the range, degree and type of morphological information of LVRS lesions, and can well predict postoperative lung function.