Objective To observe the effects of psychological intervention combined with physical training of pelvic floor muscle on psychological status and quality of life in patients with stress urinary incontinence. Methods From Jan. 2014 to Jan. 2016, 98 women with stress urinary incontinence in our hospital were selected and randomly divided into the control group (n=49) and the observation group (n=49). The control group was given physical training of pelvic floor muscle and routine nursing, and the observation group was additionally given psychological intervention based on the control group. They were treated for 8 weeks, and the self-rating depression scale (SDS) score, self-rating anxiety scale (SAS) score and incontinence quality of life questionnaire (I-QOL) score were compared between the two groups before and after treatment. Results After treatment, the SDS and SAS scores in the two groups were significantly lower than those before treatment (P<0.05), and ,the decrease degree of SDS and SAS scores in the observation group were significantly higher than that in the control group (P<0.05). The scores of behavior restriction, psychological impact and social barriers, and total score in the two groups were significantly higher than those before treatment (P<0.05), and the increase degree of the above-mentioned scores in the observation group was higher than that in the control group (P<0.05). Conclusion Psychological intervention combined with physical training of pelvic floor muscle can improve the psychological status and quality of life of patients with stress urinary incontinence.