Head and Neck Imaging

Curative Effect and Influencing Factors of Hepatectomy in the Treatment of Intrahepatic Cholangiocarcinoma

Author:WANG Xiao-yu

affiliation:Department of General Surgery, Nanyang Second People's Hospital, Nanyang 473000, Henan Province, China

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Abstract

Objective To study the curative effect and influencing factors of hepatectomy in the treatment of intrahepatic cholangiocarcinoma (ICC). Methods The clinicopathological data of 87 patients with intrahepatic cholangiocarcinoma treated in our hospital from April 2015 to April 2017 were retrospectively analyzed. All the patients were treated with hepatectomy, and the clinical effects and influencing factors were analyzed. Results Among these 87 patients, the recurrence rates of 1, 3 and 5 years were 42.53%, 66.67% and 74.71%, and the survival rate of 1,3 and 5 years were 65.52%, 40.23% and 26.44%. ICC patients with symptoms as tumor diameter>5cm, multiple tumors, lymph node metastasis, invasion of neighboring organs, positive surgical margins, preoperative seromucoid CA19-9>35U/ml, serum carcinoembryonic antigen (CEA)≤5μg/L, serum alpha fetoprotein (AFP) ≤25μg/L had worse prognoses (P<0.05). Conclusion Hepatectomy is the first choice for the treatment of intrahepatic cholangiocarcinoma, and its influencing factors are tumor diameter, tumor numbers, lymph node metastasis, invasion of neighboring organs, surgical margin, and levels of CA19-9, CEA9 and AFP.

【Keyword】Hepatectomy; Intrahepatic Cholangiocarcinoma; Curative Effect; Influencing Factors

【Chart number】R735.7;R657.3

【Document Identification Number】A

【DOI】10.3969/j.issn.1009-3257.2019.01.025