Objective To investigate the relationships and types between pulmonary ground glass nodules (GGNs) and microvessel, and explore its value in diagnosis. Methods To study retrospectively the MSCT images of 45 cases proved by operation, pathology or clinical materials. The relationships between GGN and microvessel were divided into five types. Type I: The vessel were circumvent GGN lesions．Type lI: the ovessel were normal course in the GGO. TypeⅢ: The ovessel was distortion and extension in the GGN. TypeⅣ: the vessel reached into and gived off branches in the GGO. TypeⅤ: 2 or more than 2 ovessels gived off branches and communicated with each other in the GGNs. The relationship type and pathologic of GGN were statistically analyzed. Results Of 45 GGNs ,2 were inflammation, 4 were atypical adenomatous hyperplasia (AAH), 7 were adenocarcinoma in situ (AIS), 11 were mininally invasive adenocarcinoma (MIS), 21 were invasive adenocarcinoma (IAC).Types Ⅰ-Ⅴmicrovessel relationships were observe in 3,3,12,11 and 16 GGNs.Type Ⅴ relationship was obvious one. All 16 cases of typeⅤwere IAC. There were 8 IAC, when the relationship between GGNs and microvessel. There was significant association between IAC and type ⅣandⅤof GGNs, according to statistical analysis. Statistical significance were found between 3 groups of pathology result(inflammation group, precancerosis ground, IAC ground) and microvessel(P ＜0.001). Conclusion There were different relationships between GGNs and microvessel. It is helpful for differential diagnosis by analyzing the relationships between GGNs and microvessel.