Head and Neck Imaging

The Influence of CT and Different Mannitol Application Time on the Hematoma Enlargement, Edema, AQP4, Prognosis for the Patients with Acute Intracerebral Hemorrhage

Author:YUAN Pu-jun

affiliation:Department of Intensive Care Unit, Henan Workers' Hospital, Zhengzhou 450000, Henan Province, China

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Abstract

Objective To explore the influence on the hematoma enlargement, edema, AQP4, prognosis for the patients with acute intracerebral hemorrhage by head CT+mannitol different application time. Methods 80 cases of patients with AICH were randomly divided into observation group(40 cases) and control group(40 cases). They were all tested by head CT, the control group was treated by mannitol immediately, the observation group were treated by head CT and different mannitol application. The clinical effect was observed. Results The rate of 48h hematoma enlargement, hematoma enlargement, recurrent bleeding for the observation group were lower than the control group(P<0.05). The scores of NIHSS, cephalophyma, intracranial edema and the levels of AQP4 after 1 week, 2 weeks for the observation group were lower than the control group(P<0.05). Conclusion It can increase the clinical effects for the patients with acute intracerebral hemorrhage with the help of CT and different mannitol application time, which can reduce the risk of hematoma increases, continues bleeding or rehemorrhage.

【Keyword】AICH; Head CT; Mannitol; Hematoma Increases

【Chart number】R445.3;R743.3

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2018.04.014