Head and Neck Imaging
Image Characteristics of PET-CT in Clinical Diagnosis of Dementia with Lewy Bodies
Author:HU Shu-li, CAO Hui, ZHANG Rui
affiliation:Department of Neurology, General Hospital of Shenma Medical Group, Pingdingshan 467000, Henan Province, China
PDFAbstract
Objective To investigate the clinical value and imaging features of PET-CT in the diagnosis of dementia with Lewy bodies(DLB). Methods The clinical data of 21 DLB patients admitted to our hospital from January 2013 to May 2017 were retrospectively analyzed. All patients were diagnosed by MRI and PET-CT, and their imaging features were analyzed. Results PET-CT imaging of DLB patients showed: glucose metabolism decreased significantly in bilateral occipital parietal cortex and anterior temporal gyrus, and regional glucose metabolism decreased slightly in anterior cingulate cortex and central sulcus adjacent cortex. At AUC=9.865, the sensitivity and specificity of PETCT in diagnosis of DLB were 90.47% and 95.23%, and OR (95%CI) was 1.535 (1.025- 3.166), and the sensitivity and specificity of PET-CT were significantly higher than those of conventional MRI (P<0.05). Conclusion PET-CT for DLB diagnosis has the characteristic imaging findings, and has high sensitivity and specificity.
【Keyword】Dementia with Lewy Bodies; PET-CT; Clinical Diagnosis; Image Feature
【Chart number】R742;R445.5
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2018.04.011
Chinese journal of CT and MRI
th16Volume, th 4 Issue
2018Year04Month
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