Head and Neck Imaging
Diagnostic Values of Dynamic Load CT Myocardial Perfusion Imaging in Coronary Atherosclerosis
Author:YANG Pei-ling, ZHANG Fu-quan
affiliation:Department of Cardiology, Anyang People's Hospital, Anyang 455000, Henan Province, China
PDFAbstract
Objective To explore the diagnostic values of dynamic load CT myocardial perfusion imaging (CT-MPI) in coronary atherosclerosis. Methods 60 patients with suspected coronary atherosclerosis were enrolled. The CT-MPI perfusion results and quantitative indexes [myocardial blood flow (MBF) and myocardial blood volume (MBV), time to peak (TTP)] were recorded. According to coronary arteriography, myocardial segments were divided into normal perfusion group (stenosis area<50%) and abnormal perfusion group (stenosis area >50%). The MBF, MBV and TTP were compared between two groups, and the diagnostic efficacy of CT-MPI was analyzed by ROC curve. Results CT-MPI showed that there were 35 cases with 52 vessels and 329 segments with myocardial perfusion reduction, and the abnormal rate of perfusion was 58.33% (35/60). The levels of MBF and MBV in abnormal perfusion group were lower than those in normal perfusion group, and the level of TTP was significantly longer than that in normal perfusion group (P<0.05). In level of patients, blood vessels, segment, the sensitivity of CT-MPI in the diagnosis of coronary atherosclerosis were 90%, 93.75% and 91.17%%, and the specificity were 57.50%, 85.13% and 97.21%, and the accuracy were 68.33%, 86.67% and 95.20%, and the Kappa values were 0.400, 0.634 and 0.891, and the area under the ROC curve were 0.697, 0.719 and 0.951. Conclusion Dynamic load CT-MPI has a high diagnostic value in coronary atherosclerosis and is worthy of clinical promotion and application.
【Keyword】Load; Dynamic; CT Myocardial Perfusion Imaging; CT-MPI; Coronary Atherosclerosis; Diagnostic Values
【Chart number】R541.4;R445.3
【Document Identification Number】A
【DOI】10.3969/j.issn.1672-5131.2018.04.024
Chinese journal of CT and MRI
th16Volume, th 4 Issue
2018Year04Month
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