Head and Neck Imaging

Application of Diffusion Tensor Imaging in Diffuse Axonal Injury

Author:MA Lian-ju, ZHANG Jun, LIU Ying-jun

affiliation:Department of Imaging, Beijing Shunyi District Hospital, Beijing 101300, China

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Abstract

Objective To explore the application value of diffusion tensor imaging (DTI) in diffuse axonal injury (DAI). Methods The clinical data of 36 patients with DAI (DAI group) treated in our hospital from March 2014 to March 2017 were retrospectively analyzed, and 36 healthy volunteers (control group) were examined by DTI. Image features of patients with DAI were analyzed. Fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values of region of interest (ROI) (the splenium of the corpus callosum, the internal capsule, frontal white matter, thalamus) were compared between the two groups. Results FA and ADC values of ROI (the splenium of the corpus callosum, the internal capsule, frontal white matter, thalamus) in DAI group were significantly lower than those in the control group (P<0.05). Conclusion DTI can objectively reflect the white matter damage in patients with DAI, which is of high sensitivity in the diagnosis of DAI and evaluation of the prognosis.

【Keyword】Diffusion Tensor Imaging; Diffuse Axonal Injury; FA; ADC

【Chart number】R445.2

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2018.04.009