Objective To make a thorough inquiry about the value of enhanced MRI scan in diagnosis of the corpus callosum gliomas. Methods Retrospective analysis of the clinical data and MRI data of patients in our hospital with the corpus callosum gliomas identified by surgery from February 2014 to January 2016. And the size, distribution, enhancement degree of the malignant transformation of the patients were analyzed and classified. Results In 60 cases, these tumors' location involving corpus callosum were rostrum and genu(n=40), body(trunk)(n=15), splenium(n=5). The images showed that there is a uneven long T1 and long T2 signal intensity in the tumor region, and some boundary was clear. 50 cases showed uneven enhancement, and the boundary was not regular; 10 cases were even enhancement at contrast-enhanced scan. Compared with the results of surgery, the results that the total detetion rate of the patients with the corpus callosum gliomas is 90%. Conclusion In the judging the patients with the corpus callosum gliomas, enhanced MRI scan can give a accurate location. Thus, it can be for further promotion and application in the diagnosis of the corpus callosum gliomas.