Objective To explore the effectiveness of cervical pedicle screw fixation, and to explore the accuracy and feasibility of CT measurement of cervical pedicle screw placement. Methods 96 patients with cervical pedicle screw fixation in our hospital from 2015.7 to 2014.2 were divided into hand test group and CT group, according to the time of admission, each group had 48 cases. CT group preoperatively by CT measurement of pedicle width and height determine the position of screw, hand were measured by manual measurement pedicle to determine the position of screw, observation of screw placement success rate, screw placement accuracy, record of pedicle and pedicle screw fixation time, amount of bleeding. Results CT group each screw placement time, amount of bleeding, respectively (3.78±2.45) min, (30.742±179.47) ml significantly less than in test group (4.65±2.34) min and (367.42±165.49) ml rose ml (P<0.05). CT group and the hand were measured in the C3 pedicle height, pedicle width - C6 pedicle parameter measurement value difference (P>0.05). CT group nailing high accuracy of 95.8%, the perforation rate was only 4.2%, hand were measured was 85.4%, and the perforation rate up to 14.6%, CT group than that of manual test set screw placement accuracy (P<0.05). Conclusion The clinical application of CT measurement has high accuracy, high accuracy of clinical placement, less bleeding and less time, so it can provide more accurate data for clinical individual screw placement.