Objective To investigate the accuracy rates of chest CT scan and perfusion imaging in early diagnosis and typing of central lung cancer. Methods 69 cases of patients with central lung cancer who were admitted in our hospital between March 2011 and October 2015 were selected as study subjects. Chest CT scan and perfusion imaging were performed. The CT scan findings of early central lung cancer were summarized. The diagnostic coincidence rate was calculated and was compared with the pathological results. The perfusion indexes in patients of different types were compared. Results There were lumpy or nodular soft tissue density lesions in hilar region, size in 20mm×19mm~ 50mm x 21mm, with irregular edges, presence of sentus in 30 cases and lobulated ones in 32 cases. There were pulmonary segmental bronchial stenosis in 33 cases and occlusion in 29 cases. The findings of CT plain scan combined with perfusion imaging were 39 cases with squamous cell carcinomas and 23 cases with adenocarcinomas. The coincidence rate of diagnosis and typing was 89.9% (62/69), and the difference from the pathological results was significant (P>0.05), which indicated that the accuracy was relatively higher. Conclusions Chest CT scan combined with perfusion imaging can be used to observe the shape, edge and density of central lung cancer lesions, to showed the correlation between lesions and bronchus and mediastinum as well as the status of lymph node metastasis. It is conducive to early diagnosis and typing