Objective To evaluate clinical application value of triad low-dose imaging of 64-sliced spiral CT chest pain. Methods One hundred and eight patients with chest pain admitted by the Radiology Department of the Hospital who were proposed to because of acute chest pain triad scanning were selected as research subjects, and the tube voltages were selected for patients according to different body mass indexes (BMI), the tube voltage at 120 KV was chosen if BMI was equal to or greater than 24 kg/m.The tube voltage at 100 kv was selected if the BMI was less than 24kg/m2.Both Group A and group B were satisfied, prospective heart scanning switch control technology was applied when BMI was less than 24kg/m2 (58 cases), and retrospective heart scanning switch control technology was applied when BMI of patients in Group B satisfied 24 kg/m or more (50 cases), and clinical application value of triad low-dose imaging of 64-sliced spiral CT chest pain was analyzed. Results There was no significant difference when the image quality of patients in Group A was compared to that of patients in Group B (P>0.05). There was significant difference when limited dose of patients in Group A was compared to that of patients in Group B (P<0.05). Conclusion Triad low-dose imaging of 64-sliced spiral CT chest pain delivers high clinical application value of low-dose imaging, the image quality is reliable, and it makes patients suffer from less radiation dose and has high clinical value, being worthy of promotion.