Objective To explore the value of multi-slice spiral CT and volumereconstruction posttreatment imaging in the diagnosis of lumbar compression fracture. Methods A total of 71 cases of lumbar compressibility fractures treated in our hospital from January 2017 to January 2018 were selected. All of the 71 cases were treated with CT plain scanning and post-processing image technology. The image features of lumbar compressibility fractures in the post-processing technique were summarized, and the diagnostic sensitivity and specificity of CT plain scanning and CT post-processing for lumbar compressibility fractures were compared. Results A total of 84 lumbar vertebral deformities occurred in the 71 patients, and the fracture range from the 1st lumbar vertebra to the 7th lumbar vertebra. The 1st lumbar spine is 11, the 2nd lumbar spine is 12, the 3rd lumbar spine is 18, the 4th lumbar spine is 16, the 5th lumbar spine is 17, the 6th lumbar spine is 6, and the 7th lumbar spine is 4. Vertebral body compression degree: <1/3 of the vertebral body 34 (40.47%), 1/3-1/2 of the vertebral body 39 (46.42%), >1/2 of the vertebral body 11 (13.09%). In VR post-treatment technology, 71 patients with lumbar compressive fracture all presented different degrees of vertebral wedge change, the upper margin of the vertebral body was incomplete and rough, and a few patients were associated with partial bone depression, with unclear bone trabecula structure, different degrees of density and disordered arrangement. The sensitivity and specificity of CT scanning to lumbar compressibility fracture were 80.28% and 78.87%, respectively. The sensitivity and specificity of VR posttreatment to lumbar compressibility fracture were 100.00% and 98.59%, respectively. Conclusion The diagnostic sensitivity and specificity of lumbar compressive fracture with multi-slice spiral CT volume reconstruction is high, which can be used to observe the specific condition from multiple angles.