Objective To investigate the diagnostic value of CT scan and three phase enhanced scan in endometrial carcinoma. Methods Select 53 patients with endometrial carcinoma treated in our hospital from January 2015 to December 2016, in 53 cases collect clinical data, imaging data and so on, the images of 53 patients with CT scan and CT three phase enhanced scan were analyzed by two senior imaging physicians, compare the detection rate and accuracy of endometrial carcinoma between the two methods. Results The detection rate and accuracy of CT scan for endometrial carcinoma were 75.47% and 67.92% respectively, the detection rate and accuracy of CT three phase scan for endometrial carcinoma were 98.11% and 94.33% respectively, the detection rate and accuracy of CT three phase scan in endometrial carcinoma were better than CT scan, the difference was statistically significant (P<0.001). In CT scan, in 36 patients (67.92%), the uterus showed different degrees of enlargement, with an average anteroposterior diameter (67.96±6.69)mm, at the same time, with different degrees of thickening of the uterine wall, the majority of the patients had blurred boundaries of the uterus and irregular appearance of the uterus. In 14 cases (26.41%), the cords were seen in the uterine space. In the three phase of CT enhancement, the majority of patients showed intrauterine changes, and the uterine cavity showed different degrees of enlargement, in the reinforcement process, the degree of strengthening in the uterine cavity was significantly lower than that of the papillary and irregular soft tissue in the uterine muscle wall. The arterial phase was thickened and the uterus wall was mildly strengthened, intimal enhancement was more pronounced and continued to strengthen during the venous phase, with persistent enhancement in the uterus during the delayed phase scan; In 12 cases (22.64%), the appearance of extra uterine dissemination was seen. In 6 cases (11.32%) the intestinal tract was invaded, and in 12 cases (22.64%) the images showed pelvic or retroperitoneal lymph nodes enlargement. Conclusion CT enhanced scan can display the enhanced image features of endometrial carcinoma at different stages, can improve the detection rate and accurate diagnosis rate, and is favorable for establishing a treatment plan for the clinic and improving reliable imaging data.