Objective To explore the CT diagnosis and pathological correlation of ovarian sex cord stromal tumors. Methods Retrospective analysis of CT and pathologic materials was carried out in 21 patients with ovarian sex gonad stromal tumor which confirmed by pathological examination, characteristics were analyzed. Results A total of 21 patients were unilateral tumors, 11 cases on left side, 7 cases on right side, 3 cases invaded to lower abdominal cavity, among them, 9 cases were theca cell tumor, 5 cases were granular cell tumor, 2 cases of fibroid tumor, 4 cases were leydig's cell tumor, 1 case was androblastoma. The tumor diameter were 1.9 to 14.8cm, with the the average of (7.69±2.24) cm, tumors were regular or irregular orbicular-ovate, most had clear boundary. Most theca cell tumors were solid, solid mass had mild enhancement, no enhancement in cystic and solid or cystic mass, fine tumor vascular shadow with significant enhancement could be seen in 1 case, most granular cell tumors were cystic and solid with low density, and had inhomogeneous light to mild enhancement. Fibrocellular tumors were solid mass with degeneration area, within a patchy low density area, enhanced scan showed mild enhancement. Leydigs cell tumors were solid mass and low density shadow, no reinforcement in enhanced scan; androblastoma were solid mass with even density, showed low density shadow, enhanced scan were mild enhancement. 2 patients were complicated with pyoperitoneum. Conclusion The location, property and size of ovarian sex cord stromal tumors can be judged according to CT findings, the accuracy is high, but the diagnosis should be based on the pathological results as the gold standard.