Head and Neck Imaging

MR-ASL Evaluation of Cerebral Blood Flow in Children with Cerebral Palsy Before and After Operation*

Author:YU Yang, XU Jing-xuan, WANG Yun-ling,et al.

affiliation:Department of Radiology, The second Affiliated Hospital of Xinjiang medical University, Urumqi 830011, Xinjiang Province, China

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Abstract

Objective Comparison of changes in cerebral blood flow (CBF) between normal children and cerebral palsy children by using arterial spin labeling (ASL), Depament of Radiology, The second Affiliated Hospital of Xinjiang medical University,before and after the cervical perivascular sympathectomy. Methods Using Achieva/Intera PHILIPS 3.0 T magnetic resonance imaging scan 30 normal children and 30 unilateral spastic cerebral palsy children who underwent cervical perivascular sympathectomy preoperative one week and postoperative 14 days in regular sequence, DWI, ASL and other sequences. The CBF value of different areas of the clients was obtained by MriCloud post-processing workstation, which include Bilateral of frontal lobe, the temporal lobe, the parietal lobe. Central front return,Inner sac region,The basal ganglia,The thalamus,The cerebellum were compared between two groups, A paired t-test was used for statistical analysis. Results In comparison to the control group. The CBF values in the patient group decreased. There were significant differences between two groups in Cerebral cortex, anterior central gyrus, basal ganglia, inner capsule, cerebellum in the affected side,children with cerebral palsy had improved Cerebral blood flow in above areas after the cervical perivascular sympathectomy. Conclusion ASL found that cervical perivascular sympathectomy is an effective treatment of cerebral palsy surgery,And can significantly improve the CBF of children with cerebral palsy,improving cerebral ischemia and hypoxia,relieve the clinical symptoms of children.

【Keyword】MR Imaging; Arterial Spin Labeling; Cervical Perivascular Sympathectomy; Cerebral Palsy

【Chart number】R445.2;R748

【Document Identification Number】A

【DOI】10.3969/j.issn.1672- 5131.2017.12.001