Objective To assess the value of the identification and characterization of GdEOB-DTPA -MRI enhanced Hepatobiliary phase which have effect on cirrhosis nodules and small hepatocellular carcinoma. Methods Twenty patients of cirrhosis who had MRI scan, Gd-EOB-DTPA dynamic enhanced scan and Hepatobiliary stage enhanced scan. Magnetic resonance images were analyzed, all patients who had Magnetic resonance imaging (MRI) will have biopsy or surgical pathology results within 4 weeks. Besides, imaging diagnosis and surgical pathology results were control. Results 86 nodules were detected in twenty patients of cirrhosis, 17 cases of small hepatocellular carcinoma were detected through conventional unenhanced scan and enhanced scan while 21 cases of small hepatocellular carcinoma were detected. Through Hepatobiliary phase enhanced scan , the sensitivity and specificity of small hepatocellular carcinoma had improved, which has only three characteristics of malignant nodules in the liver and gallbladder period. Conclusion Contrast to cirrhosis nodular regenerative/hyperplastic nodules and early HCC, the sensitivity and accuracy of Hepatobiliary phase enhanced scan are higher than dynamic enhanced MRI scan. Gd-EOB-DTPA－enhanced MRI scan can early detect malignant nodules and cirrhosis of liver cancer. Gd-EOB-DTPA is recommended to apply to enhancement MRI examination in patients with cirrhosis.