Objective To assess the clinical value of dual energy computed tomography (DECT) color-coded map for detect uric acid deposition. Methods 24 cases of gout patients enrolled in the study, 13 cases with a history of gout (according to the American College Rheumatology Criteria), clinical suspicion of gout were 6 cases, the other 5 cases did not take into account the possibility of gout before the examination. DECT dual-energy scanning was conducted to obtain 140,80 kvp and hybrid energy diagram(equivalent to conventional energy120 KV single image) simultaneously at different checkpoints. Pseudo-color coded map was derived after processing by DECT Gout software. Two physicians independently evaluate the average weighted 120 kvp diagrams and pseudo-color coded map respectively, mainly observing the location, number and size of urate deposition. Results All of the 24 cases have showed the different location, number, size of urate deposition, DECT color-coded map has represented a greater number of urate deposition than mixing energy tomography (equivalent to conventional energy 120 KV single image) and have a stronger capability to display more urate deposition(P<0.05). For 13 cases of gout confirmed by clinical,DECT was more excellent for demonstrating the urate deposition in tiny subclinical parts for the 13 cases of gout confirmed by clinical and could make a definitive or suggest diagnosis for the 6 cases of clinically suspicious and five cases of gout patients not previously taken into account the possibility of gout.Two physicians to assess urate deposition numbers which used of DECT has no significant difference (P> 0.05), and the use of hybrid energy imaging (equivalent to conventional energy 120 KV single image) has significant difference (P <0.05). Conclusion DECT has stronger ability in displaying urate deposition, further more,it can be used as screening of gout. DECT is of clinical worthy in a comprehensive assessment of the clinical condition and clinical application.