Objective To compare the diagnostic value of ultrasound, CT and MRI in endometrial carcinoma staging, mucosal invasion and lymph node metastasis. Methods The clinical data of 80 patients with endometrial carcinoma confirmed by pathology and treated in our hospital from January 2010 to April 2015 were retrospectively analyzed. All patients received ultrasound, CT and MRI examination before operation and the imaging data were complete. The value of different imaging methods in the diagnosis of endometrial staging, mucosal invasion and lymph node metastasis was compared. Results The conformity of MRI and pathological staging was the highest which was 97.5%; In 80 cases, 58 cases were confirmed with myometrial invasion by postoperative pathology. The preoperative ultrasound in 45 cases indicated invasion, CT in 44 cases indicated invasion and MRI in 52 cases indicated invasion. 14 cases were confirmed with cervical invasion. 16 cases, 12 cases and 15 cases were respectively detected by ultrasound, CT and MRI. Postoperative pathology showed lymph node metastasis in 9 cases. 2 cases, 8 cases and 10 cases were detected by ultrasound, MRI and CT respectively. Conclusion MRI is of the best effect in the evaluation of preoperative staging of endometrial carcinoma, mucosal invasion and lymph node metastasis in, followed by CT and ultrasound is the lowest.