Head and Neck Imaging

The Value of CT Perfusion to Predict the Response of Synchronous Radiochemotherapy for Middle-advanced Cervical Squamous Cancer

Author:YU Ying-ying, WEN Zhi, HAN Wen-guang, et al.

affiliation: Department of CT Room, Xin Jiang Tumor Hospital of Xinjiang Medical University, Urumchi 830011, Xin Jiang, China

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Abstract

Objective To evaluate the value that CT perfusion parameters to predict the response of synchronous radiochemotherapy for middle-advanced cervical squamous cancer. Methods 44 patients with cervical squamous cancer later than stage ⅡB were included in this study.They were followed up for 1 year. According to the RECIST, patients were divided into the responders group and non-responders group. Perfusion parameters of the two groups were compared. The perfusion parameters that may be effective were analysed by using ROC curve. Results 1.There were significant difference between two groups in BV and PMB. The BV and PMB in patients who received effective response were greater than patients in other groups. There were no significant difference in BF and MTT and TTP between two groups. 2.Analysed by ROC curve, the area under curve of BV were bigger than that of PMB. It counld conclude the diagnostic potency of BV higher than that of PMB. Conclusion CT perfusion could predict the response of synchronous radiochemotherapy for middle-advanced cervical squamous cancer.

【Keyword】Cervical Cancer; Synchronous Radiochemotherapy; CT Perfusion; Response Evaluation

【Chart number】R445.3;R737.33

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2017.02.023