Head and Neck Imaging
The Effect of Atorvastatin on Carotid Plaque Neovascularization by Contrast-Enhanced Ultrasound and CTA*
Author：HAN Yan-ni, ZHONG Jie-yu, DONG Li-cong,et al.
affiliation： Department of Imaging, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
PDFAbstract
Objective To evaluate the efficacy of atorvastatin in the treatment of carotid plaque neovascularization by contrast-enhanced ultrasonography(CEUS) and CTA. Methods All patients were treated with atorvastatin (20 mg/d) regularly. Blood lipid, routine ultrasound, CEUS and CTA were used to evaluate the relative indexes before and after treatment. Results 34 patients were enrolled. The plaques score, the intensity of enhancement (EI), the area under the curve (AUC) and CT value significantly decreased after treatment (P<0.05). And there were significant differences in plaque score, intensity of enhancement (EI), area under the curve (AUC), and plaque CT value at 6 months after the treatment, than those at 3 months after treatment. No end-point events or serious adverse events were observed in each group. Conclusion Ultrasonography and CTA can be used to evaluate the clinical risk of carotid atherosclerotic plaques and the therapeutic effect of statins.
【Keyword】Carotid Arteries; Plaques; CEUS; CTA; Atorvastatin
【Chart number】R543.4
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2017.02.010
Chinese journal of CT and MRI
th15Volume， th 2 Issue
2017Year02Month
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