Head and Neck Imaging

Study of the Distribution Featuresof Tophus in Foot using Dual-energy Computed Tomography*

Author:CHEN Qian, CHEN Xing-guo, FENG Yuan, et al.

affiliation: Department of Radiology, Nanjing First Hospital, NanjingMedical University, Nanjing 210006, Jiangsu Province, China

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Abstract

Objective To evaluate the distribution of tophus in foot using dual-energy CT (DECT)and to explore the pathogenesis of gout. Methods Fifty-six patients with gout had DECT scanning of both feet. The sites of tophus deposition were categorized into groups of joint, ligament/tendon and they were recorded and analyzed in order. Results The DECT scans showed tophus involving 51/56 (91.1%) patients. In the group of joint, gout affected the first metacarpophalangeal joint (75%, 73/198) mostly, followed bythe ankle joint (33.9%, 32/198).In the group of tendon/ligament, Achillestendon was the most commonly involved (39.3%, 37/99), followed bythe peroneal tendons (16.1%, 14/99). Conclusion In foot, tophus is commonly deposited at the first metacarpophalangeal joint and Achillestendon. The patterns of tophus deposition suggest that anatomical location, biomechanical strain or other local factors may contribute to the distribution of tophus.

【Keyword】Dual-energy CT; Gout; Tophus

【Chart number】R445.3;R589.7

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2017.02.035