Head and Neck Imaging
Imaging Diagnosis and Differential Diagnoisof Dysembry-oplastic Neuroepithelial Tumor*
Author:LU Fei-fei, XIAO Hui, YU Hao,et al.
affiliation:Department of Imaging, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, Fujian Province, China
PDFAbstract
Objective To analyze the imaging features and pathological features of intracranial Dysembryoplastic neuroepithelial tumor, so as to improve the diagnostic accuracy of the tumor. Methods 11 cases with pathologically proved DNET were retrospectively reviewed,included 3 cases with CT scan (2 cases with CT and MR scan), 10 patients with MRI scan, 7 cases with enhanced MR scan, 5 cases with MRS scan and 3 cases with 18 F-DPG PET. Results This group were single lesions, located in the supratentorial region and involved the cerebral cortex,including temporal lobe(3 cases), parietal lobe(1 case), frontal lobe (3 cases), insular lobe(1 case), occipital lobe(2 cases), and cerebellar hemisphere (1 case). The lesions showed cerebriform (5 cases),wedge-shaped (5 cases), irregular-shaped (2cases). Hypodensity was seen on CT in all cases, except one of mixed hypo and isodensity, bone thinning of the adjacent calvaria could be seen in 2 cases. Histologically, the DNT were classified into two subtypes:complex form (n=5, 4 cases showed a uniform thickness of wire like separated syndrome, 3 cases with intramural nodule) and simple form (n=6,2 cases showed a uniform thickness of wire like separated syndrome). 8 cases showed cystic changes on MRI. All lesions were hypointense on T1- weighted images and hype rintense on T2-weighted images except two of mixed hypo and isodensity on T1-weighted images and mixed hype and isodensity on T2-weighted images. On T2-FLAIR, 8 cases appeared visible hyperintense ring sign in the tumor periphery, 2 cases appeared mixed hypo and isodensity. On DWI, 8 cases were low signal, 2 cases showed slightly higher signal.Most of the lesions were not enhanced, but the wall nodules were slightly enhanced. 2 cases of internal lesions were scattered in small spot strengthening. There were no edema around all cases except 2 cases. On MR spectroscopy (MRS), The choline (Cho) peak was slightly higher than that of the contralateral normal brain tissue, and there was no significant reduction in N-acetyl aspartate (NAA peak). PET examination showed a low metabolism. Conclusion The imaging features of the intracranial Dysembry oplastic neuroepithelial tumor have certain characteristics, and the diagnostic accuracy can be improved by using the multi-modality imaging method.
【Keyword】Dysembryoplastic Neuroepithelial Tumor; CT; MR
【Chart number】R739.4
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2017.02.047
Chinese journal of CT and MRI
th15Volume, th 2 Issue
2017Year02Month
Related articles