Influence of Mannitol on Hematoma Enlargement and Prognosis in Treating Early Cerebral Hemorrhage

Author:REN Jie

affiliation:Department of Neurology, Chinese Medicine Hospital of Sui County, Shangqiu 476900, Henan Province, China

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Abstract

Objective To investigate the influence of mannitol on controlling hematoma enlargement and improving prognosis in treating early cerebral hemorrhage. Methods A total of 80 cases with cerebral hemorrhage in our hospital from May 2015 to June 2016 were selected and divided into two groups, 40 cases in each group. Control group was given mannitol treatment 6h after onset and observation group was given mannitol treatment within 6h. Compare the treatment effect and hematoma enlargement rate. Results There were 9 cases of hematoma enlargement in control group, hematoma enlargement rate was 22.50%, there were 3 cases of hematoma enlargement in observation group, hematoma enlargement rate was 7.50%, hematoma enlargement rate of observation group was lower than control group, the difference was statistic significant (P<0.05), total efficiency of observation group (90.0%) was higher than control group (72.5%), the difference was statistic significant (P<0.05). Conclusion The application of mannitol in treating early cerebral hemorrhage can improve clinic effect, lower hematoma enlargement rate and is worthy of clinic application.

【Keyword】Hematencephalon; Early Stage; Mannitol; Hematoma Enlargement; Prognosis

【Chart number】R74;R54

【Document Identification Number】A

【DOI】10.3969/j.issn.1009-3257.2017.04.014