Objective To analyze the effect of video health education on disease cognition degree and medication compliance of young patients (age>18) with hypertension. Methods A total of 84 young patients with hypertension in our hospital were taken as the clinical research objects, and they were randomly divided into control group (41 cases) and observation group (43 cases). The conventional health education was given to the control group, and the video health education which presented in various forms was given to the observation group. One week after treatment, the disease cognition degree and medication compliance of the two groups were evaluated. Results One week after treatment, the pass rate and excellent rate of cognition degree in the control group were respectively 90.2% and 65.8% which were significantly lower than those in the observation group 100.0% and 95.3%(P<0.05), the excellent rate of medication compliance in the control group was 75.6% which was obviously lower than that in the observation group 97.7%, and their difference was statistically significant(P<0.05). Conclusion Video health education which has the advantages of easy to operate and low requirements, can effectively improve the disease cognition degree and medication compliance of young patients with hypertension. Thus, it is worthy of application.