Objective To provide the basis for early diagnosis, imaging of ischemic bowel disease caused by superior mesenteric artery disease was analyzed with multi-slice spiral CT retrospectively. Methods 6 cases of intestinal ischemia from August 2012 to August 2015 in this hospital onfirmed by clinical were collected, multi-slice spiral CT was proceed for a full abdominal CT scan, among of them 4 cases were enhanced scanning. Superior mesenteric artery was evaluated with cross section original CT image and variety processing technology. Results 3 cases of 6 patients were acute intestinal ischemia, with clinical manifestations of acute abdominal pain, and all 3 cases were superior mesenteric arterial thrombosis. CT enhancement scan shows thrombosis of the superior mesenteric artery with intraluminal filling defects. Mild to moderate narrowing were seen, degree of stenosis was between about 50%.The other 3 cases of chronic intestinal ischemia were characterized by chronic abdominal pain associated with eating, with long distance or local calcification stenosis of superior mesenteric artery. 2 cases of 6 occurred in mild cases of intestinal obstruction, with intestinal gas fluid expansion and thickening blur.6 cases of patients with non-surgical treatment have curative effect. Conclusion MSCT can give clear early diagnosis of ischemic bowel disease caused by superior mesenteric arterial lesions, which is important for guiding significance for clinical treatment.