Objective To analyze the CT manifestation of the solid pseudopapillary tumor of pancreas (SPTP) and to explore the diagnostic value of CT. Methods Both corresponding literatures review and retrospective method were applied to analyze the data of CT images from five cases of SPTP confirmed by operation and pathology. Results 5 female patients, aged from seventeen to forty-five were proved single lesion with tumor diameter of 5-12cm. Among the five cased three focued on the head of pancreas, one on the pancreatic body, and the last on the pancreatic body-tail. The lesion presented as round or oval in shapes which oppress surrounding round tissues and organs to a certain extent. Solid and cystic structures were exposed within the neoplasm.1 tumor was composed of similar proportions of solid and cystic parts, and 4 cases were mainly composed of cystic parts. Reinforced performance for a substantial part of the arterial phase leads to a slight-moderate enhancement, and progressive enhancement was occurred in the portal venous phase. Enhanced solid part bears a little lower enriched degree than normal pancreatic parenchyma. The cystic portions appeared hypo-attenuation on both pre-and post-contrast views Homogeneously reinforcement was found in the fibrous capsule. Of all five masses, 1case was incomplete capsule, 2 cases were calcified capsule, 1with slight pancreatic duct and the last one with the low density in the latter part of the right lobe of liver (S6). The reexamine eight months after the treatment, the lesion was about 3.6mm larger than before. Conclusion The CT findings of SPTP is helpful to the accurate preoperative diagnosis of the disease.