Imaging Features of Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor in Pelvic Bones: Correlations with Clinic and Pathological Findings

Author:GU Ling-jing, ZENG Hui

affiliation: Department of Radiology, Zhuhai People’s Hospital, Zhuhai, Guangdong, Province, 519000, China

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Abstract

Objective To discuss the imaging findings of ES/pPENT in pelvic bones and to improve the cognition. Methods Eight patients with ES/pPENT in pelvic bones with pathologically proved were retrospectively analyzed for their clinical, pathologic and radiologic features. All the patients were underwent X-ray examination, 4 patients performed CT examination, and 7 patients performed MR. Imaging findings include: the location, number, bone destruction, periosteum reaction and bone, soft tissue mass, and enhancement mode. Pathological examination of the observed indicators include morphology and immunohistochemistry. Results 7 cases showed osteolytic bone destruction; and only one case showed sclerosis bone destruction .7 cases showed huge and uneven density soft tissue mass with bone destruction, and in 6 cases which the maximum diameter of the tumor were more than 8cm.4 cases involved the adjacent joints; MR imaging showed line dark signal interval in soft tissue mass on T2WI, with partly enhancement. 6 cases was found with metastases, and 3 were in pulmonary. Immunohistochemical CD99 of all cases were positive expression. Conclusion ES/pPENT shows certain characteristics, but lacks the specificity. Pathological examination is mandatory to confirm the diagnosis. For young patients with bone destruction and soft tissue mass, the chance of ES/ pPNET should be considered.

【Keyword】Ewing’s Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Pelvic Bones; Tomography, X-ray Computed

【Chart number】R445;R738.1

【Document Identification Number】A

【DOI】10.3969/j.issn.1009-3257.2016.01.018