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补心益肾化痰汤联合丙戊酸治疗成人癫痫的效果观察

作者:陈 燕

所属单位:河南省新乡市第二人民医院神内一科 (河南 新乡 453000)

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摘要

目的 观察补心益肾化痰汤联合丙戊酸治疗成人癫痫的效果。方法 选取2016年5月至2017年5月医院收治成人癫痫患 者96例作为研究对象,根据随机数表法分为观察组和对照组,每组48例,对照组给予丙戊酸治疗,观察组在对照组 基础上使用补心益肾化痰汤联合治疗。比较两组临床治疗疗效,统计两组治疗前后癫痫患者生活质量量表QOLIE-31 评分。结果 观察组临床治疗总有效率95.74%高于对照组73.91%(P<0.05);观察组治疗后生活质量量表评分高于对 照组(P<0.05)。结论 补心益肾化痰汤联合丙戊酸治疗成人癫痫治疗效果优于单用丙戊酸,可以有效提高患者生活 质量。

Objective To observe the effects of Buxin Yishen Huatan decoction combined with valproic acid in the treatment of adult epilepsy. Methods A total of 96 patients with adult epilepsy admitted to the hospital from May 2016 to May 2017 were selected for the study and were divided into observation group and control group according to the random number table method, with 48 cases in each group. Control group was treated with valproic acid, and observation group was given Buxin Yishen Huatan decoction for combined therapy on the basis of control group. The clinical efficacy in the two groups was compared, and the quality of life scale QOLIE-31 score of patients with epilepsy was counted in the two groups before and after treatment. Results The total effective rate of clinical treatment in observation group was higher than that in control group (95.74% vs 73.91%) (P<0.05). The score of quality of life scale in observation group after treatment was higher than that in control group (P<0.05). Conclusion Buxin Yishen Huatan decoction combined with valproic acid has better effects than valproic acid in the treatment of adult epilepsy, and it can effectively improve the quality of life of patients.

【关键词】癫痫;补心益肾化痰汤;丙戊酸

【中图分类号】R742.1

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2019.03.026

前言

癫痫作为一种慢性疾病,发病率仅次于脑卒中, 属于神经系统第二常见疾病,复杂程度高,目前在 我国约有600多万患者,癫痫具有反复性、多发性等 特点,严重危害患者的身心健康[1]。丙戊酸可给予脑 保护等对症措施,但无法控制发作尤其对发作频繁 患者,且无法预防复发,长期使用还会出现不良反应 及副作用[2]。目前中医临床上常采用化痰逐瘀汤配合 西药治疗癫痫,取得不错的效果。本研究探究补心益 肾化痰汤联合丙戊酸治疗成人癫痫的效果,现分析如 下。